Endolymphatic sac tumors: histopathologic confirmation, clinical characterization, and implication in von Hippel-Lindau disease

The Laryngoscope
C A MegerianJ B Nadol

Abstract

The term "endolymphatic sac tumor" (ELST) was coined to identify the likely origin of aggressive papillary tumors of the temporal bone. To evaluate the validity of this designation, the temporal bone collection at the Massachusetts Eye and Ear Infirmary was accessed in an effort to determine the pathologic relationship between these tumors and the endolymphatic sac. The search resulted in the identification of a de-novo papillary epithelial lesion arising within the confines of the endolymphatic sac in a patient with von Hippel-Lindau (VHL) disease who harbored a large, destructive ELST in the opposite temporal bone. This finding provides the most substantial evidence to date regarding the origin of the ELST and the accuracy of its nomenclature. Seven additional clinical cases of ELST were identified and analyzed in order to define the natural history of these tumors. All patients had a history of sensorineural hearing loss diagnosed an average of 10.6 years prior to tumor discovery. The presence of a polypoid external auditory canal mass, facial paralysis, and evidence of a destructive mass arising on the posterior fossa surface of the temporal bone were common physical and radiographic findings. The management of these patien...Continue Reading

References

Jan 1, 1976·Clinical Otolaryngology and Allied Sciences·V J Hyams, L Michaels
Nov 1, 1975·Archives of Otolaryngology·H E StoneR D Bell
May 1, 1992·The Journal of Laryngology and Otology·T L BlamiresD A Moffat
Jan 1, 1990·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·H J AltermattJ A Laissue
Jan 1, 1989·Acta Oto-laryngologica·C ErwallJ Wroblewski
Jan 1, 1989·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·J M PalmerR L Harper
Jun 1, 1989·The Laryngoscope·J F KvetonD S Poe
Jul 19, 1989·Journal of the National Cancer Institute·K ToryF F Marshall
Sep 1, 1989·AJR. American Journal of Roentgenology·K C Funk, J P Heiken
Sep 1, 1989·Neurosurgery·R G EllenbogenW J Kupsky
Nov 1, 1988·The Annals of Otology, Rhinology, and Laryngology·T L EbyU Fisch
Oct 1, 1988·The American Journal of Surgical Pathology·M J GaffeyM R Wick
Dec 1, 1986·Brain : a Journal of Neurology·S M HusonD A Compston
Apr 1, 1986·Archives of Otolaryngology--head & Neck Surgery·D Bagger-SjöbäckH Rask-Anderson
Apr 1, 1974·The Journal of Laryngology and Otology·K HarrisonN Greenwood
May 1, 1972·Cancer·C V WetliK Gerston
Jun 1, 1980·American Journal of Clinical Pathology·G F MurphyJ B Nadol
Aug 1, 1983·The Laryngoscope·R A JahrsdoerferJ B Powell
Jun 1, 1983·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·D E SchullerW J Miller
Jun 1, 1980·The American Journal of Surgical Pathology·B R Krawiss, J Ludwig
Jan 1, 1993·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·D S PoeJ F Kveton
Sep 1, 1961·The Annals of Otology, Rhinology, and Laryngology·K H SIEDENTOP, C JEANTET

❮ Previous
Next ❯

Citations

Feb 18, 2014·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·S RaghunandhanMohan Kameswaran
Jul 6, 2014·Case Reports in Otolaryngology·Emanuele FerriIda Pavon
Dec 15, 2006·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·B SchickW Draf
Apr 2, 2008·Journal of Neurosurgery·Russell R LonserAlexander O Vortmeyer
May 2, 2008·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·Rodney C DiazWayne T Shaia
Mar 5, 2011·AJR. American Journal of Roentgenology·Philip R ChapmanAsim K Bag
Aug 8, 2001·Auris, Nasus, Larynx·S InanliR Ahýskalý
Jun 17, 2006·Advances in Anatomic Pathology·Michele BiscegliaBruce M Wenig
Apr 25, 2008·Advances in Anatomic Pathology·Bahig M ShehataHaynes Robinson
Sep 25, 2010·Acta neurochirurgica·Mette Bertelsen, Michael Kosteljanetz
Dec 25, 2010·HNO·V VielsmeierM Huber
Sep 14, 2011·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Marie Louise Mølgaard PoulsenMarie Luise Bisgaard
Nov 12, 2005·Neurosurgical Review·Hubert LöwenheimMarcos Tatagiba
Sep 23, 2003·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Robert A Williamson, Newton J Coker
May 1, 2002·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Cliff A MegerianMichael E Glasscock
Jul 9, 2004·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Stephen RodriguesJenny Turner
Sep 9, 2004·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Nicholas C BambakidisRobert A Ratcheson
Sep 9, 2004·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Michael E KupfermanKen Kazahaya
Jul 15, 2005·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Anirvan BanerjeeM D Atlas
May 21, 2013·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Matthew L CarlsonGeorge B Wanna
Sep 3, 1998·Histopathology·G KempermannB Volk
Nov 28, 2001·Current Opinion in Neurology·K B Sims
Jun 11, 2004·The New England Journal of Medicine·Russell R LonserEdward H Oldfield
Aug 27, 2005·Journal of Neurosurgery. Spine·Nicholas C BambakidisRobert A Ratcheson
Aug 19, 2007·Journal of Neurosurgery·Jay JagannathanH Jeffrey Kim
Sep 24, 2005·Journal of Neurosurgery·Timothy W A VogelZhengping Zhuang
Sep 8, 2009·Neuroimaging Clinics of North America·Cheng Kang Ong, Vincent Fook-Hin Chong
Jun 5, 2007·Otolaryngologic Clinics of North America·Cliff A Megerian, Maroun T Semaan
Jul 29, 2004·The Laryngoscope·Marlan R Hansen, William M Luxford
Oct 31, 2014·Diagnostic Cytopathology·Jennifer P BynumSyed Z Ali
Jun 11, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Kevin A PengAkira Ishiyama
May 9, 2006·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·D P MuzumdarN Goel
Feb 10, 2006·Auris, Nasus, Larynx·Tadashi WadaSugata Takahashi
Jun 9, 2004·Neuroimaging Clinics of North America·James G Smirniotopoulos
Jan 9, 2004·Acta Oto-laryngologica·Kenneth O DevaneyAlessandra Rinaldo
Apr 14, 2015·Head & Neck·Birke BauschUNKNOWN International Endolymphatic Sac Tumor (ELST) Consortium
Jun 23, 2016·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Arturo Mario PolettiAntonio Mazzoni
Feb 5, 2015·Otolaryngologic Clinics of North America·Cameron C WickCliff A Megerian
Nov 14, 2014·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Heather HampelUNKNOWN Guideline Development Group, American College of Medical Genetics and Genomics Professional Practice and Guidelines Committe
Jun 9, 2016·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Joseph B Nadol
Jun 13, 2008·Otolaryngologia polska. The Polish otolaryngology·Anna SzymańskaAgnieszka Trojanowska
Oct 3, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Orin G BlochAndrew T Parsa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Related Papers

JAMA : the Journal of the American Medical Association
T J ManskiE Oldfield
Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
C A MegerianM E Glasscock
© 2021 Meta ULC. All rights reserved