Endometrial cancer in the elderly: does age influence surgical treatments, outcomes, and prognosis?

Menopause : the Journal of the North American Menopause Society
Meriem KoualAnne-Sophie Bats

Abstract

To compare clinicopathological characteristics, surgical outcomes, and survival rates for nonelderly (<75 years old) and elderly (≥75 years old) women with endometrial cancer (EC). This retrospective study included consecutive patients who underwent surgery for EC at the gynecologic-oncologic surgery department of Hôpital Européen Georges-Pompidou (Paris, France) from January, 2002 to December, 2015. Independent-group t tests and chi-square tests were used to compare elderly and nonelderly women. Survival rates were compared using log-rank (Mantel-Cox) tests. In the nonelderly and elderly groups, the mean age at EC diagnosis was 63 (range 33-74) and 81 (range 75-95) years, respectively. Compared with nonelderly patients, elderly patients (n = 104) presented with more advanced disease and more aggressive histological findings. However, surgical approaches did not differ between the two groups, and 76% of all patients underwent minimally invasive surgery. Pelvic lymphadenectomy was performed in 65% and 44% of nonelderly and elderly patients, respectively (P = 0.01), whereas para-aortic lymphadenectomy was performed in 26% and 9% of nonelderly and elderly patients, respectively (P < 0.0001). The incidence of perioperative complica...Continue Reading

References

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Citations

Aug 8, 2018·Menopause : the Journal of the North American Menopause Society·Junnan WangZheng Xu
Aug 20, 2019·World Journal of Clinical Cases·Mian-Li ZhouHui Mao
Aug 22, 2018·Menopause : the Journal of the North American Menopause Society·Meriem KoualFabrice Lécuru
Jul 1, 2019·Archives of Gynecology and Obstetrics·Ling ZhaoJiali Luo
Jun 21, 2020·Surgical Oncology·Judicael HottonAnne-Sophie Bats

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