Endometrial cancer in women 40 years old or younger

Gynecologic Oncology
L R DuskaA F Fuller

Abstract

The aim of this study was to characterize endometrial cancer in women 40 years of age and younger, with special attention toward body-mass index (BMI). A retrospective review of women age 40 and under with endometrial cancer was performed. Patients were identified via tumor registry data as well as a search of pathology department diagnoses over the dates 1980-1998. Data were abstracted regarding tumor grade and histology, stage, treatment, smoking, use of oral contraceptives, BMI, medical and family history, parity, and survival. Data were also collected with regard to uterine conservation and pregnancies following endometrial cancer diagnoses. Ninety-five patients were identified. The age range was 24-40 years (median 37) with BMI ranging from 17.5 to 63.6 (median 28.4). Forty-eight patients (52%) were not obese, with BMI < 30. Seventy-six patients (80%) had stage I disease and 60 patients (63%) had grade 1 disease. All but 4 patients had endometrioid histology. Women with BMI < 25 were more likely to have advanced disease (P = 0.04) and more likely to have high-risk histology (P = 0.02). Of the 4 patients with high-risk histology (clear cell or serous papillary), all had BMI < 25. Twelve patients were treated medically rathe...Continue Reading

References

Nov 1, 1992·Gynecologic Oncology·D J HetzelK C Podratz
Feb 1, 1987·American Journal of Obstetrics and Gynecology·J D JefferyG C Stuart
Feb 1, 1985·Gynecologic Oncology·J V BokhmanA S Vishnevsky
Apr 1, 1968·Cancer·R L Kempson, G E Pokorny
May 1, 1968·Obstetrics and Gynecology·E P Peterson
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
May 1, 1995·Obstetrics and Gynecology·A L PisaniB Y Karlan
Apr 1, 1995·Obstetrics and Gynecology·G GitschN F Hacker
Mar 1, 1996·The American Journal of Clinical Nutrition·R Ballard-Barbash, C A Swanson
Mar 10, 1998·Obstetrics and Gynecology·E R Evans-MetcalfS P Baker

❮ Previous
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Citations

Jan 25, 2012·Obstetrics and Gynecology·Alaina J BrownKathleen Schmeler
Jan 27, 2005·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·M YasudaT Shinozuka
Dec 21, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·G CormioL Selvaggi
Jul 9, 2010·Obstetrics and Gynecology International·Ying Zhang, Jian Wang
Jan 1, 2010·Clinical Medicine Insights. Case Reports·Anis FadhlaouiAnis Chaker
Mar 1, 2014·Archives of Pathology & Laboratory Medicine·Karuna Garg, Robert A Soslow
Aug 3, 2012·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Leonardo Saúl Lino-SilvaMaría Delia Pérez-Montiel
Jun 15, 2014·Gynecologic Oncology·William M BurkeUNKNOWN Society of Gynecologic Oncology Clinical Practice Committee
Aug 25, 2009·Fertility and Sterility·Ivan MazzonGiovanni Scambia
Jan 16, 2007·Archives of Gynecology and Obstetrics·Agnaldo L Silva-FilhoJoão Gilberto Castro e Silva
Apr 13, 2011·Taiwanese Journal of Obstetrics & Gynecology·An-Shine ChaoHsin-Shih Wang
Dec 19, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Fumitaka SaitoHidetaka Katabuchi
Jun 9, 2014·Journal of the Chinese Medical Association : JCMA·Hei-Yu LauYi-Jen Chen
Dec 5, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N ColomboUNKNOWN ESMO-ESGO-ESTRO Endometrial Consensus Conference Working Group
Dec 20, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Nicoletta ColomboUNKNOWN ESMO-ESGO-ESTRO Endometrial Consensus Conference Working Group
Jan 17, 2012·Hematology/oncology Clinics of North America·Jeanne CarterLari Wenzel
Nov 3, 2015·Taiwanese Journal of Obstetrics & Gynecology·Hei-Yu LauKung-Liahng Wang
Jan 22, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Yoshino KinjyoYoichi Aoki
Apr 7, 2015·Journal of Minimally Invasive Gynecology·Virginia BenitoAmina Lubrano
Sep 26, 2006·Gynecologic Oncology·Theodoros MaltarisHeinz Koelbl
Apr 25, 2006·Gynecologic Oncology·Susan C ModesittStephen Wyatt
Jul 30, 2005·Gynecologic Oncology·Yuh-Cheng YangKung-Liang Wang
Sep 12, 2015·Lancet·Philippe MoriceEmile Darai
Mar 18, 2011·American Journal of Obstetrics and Gynecology·Ramez N EskanderRobert E Bristow
Oct 18, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Jeong-Yeol ParkJoo-Hyun Nam
Jul 30, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Lu-Hong LiZhi-Chao Li
Nov 3, 2010·Gynecologic Oncology·Giuseppe LaurelliStefano Greggi
Aug 28, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Polat DursunAli Ayhan
Jan 28, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jason D WrightThomas J Herzog
Apr 25, 2014·Journal of Gynecologic Oncology·Jayeon KimJennifer E Mersereau
Jun 27, 2017·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Sung Woo KimYoung Min Choi
May 16, 2009·International Journal of Surgical Pathology·Maria Luisa CarcangiuPaolo Sala
Mar 3, 2018·Cancer Causes & Control : CCC·Sarah M TemkinAnne-Michelle Noone
Jan 20, 2018·Japanese Journal of Clinical Oncology·Hidetaka NomuraNobuhiro Takeshima
Aug 10, 2018·International Journal of Cancer. Journal International Du Cancer·Robert NeffPaul J Goodfellow
Apr 24, 2012·Journal of Gynecologic Oncology·Joshua P Kesterson, James Fanning
Oct 4, 2005·Obstetrics and Gynecology·Christine WalshIlana Cass

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