Endometrial cancer occurence five years after breast cancer in BRCA2 mutation patient

Obstetrics & Gynecology Science
Sang Eun OhMin Kyu Kim

Abstract

We recently experienced a case of endometrial cancer 5 years after the diagnosis of breast cancer in a patient with a mutation in the BRCA2 gene. A 55-year-old Korean woman who had a past history of breast cancer in her 50s underwent an operation for endometrial cancer. Final pathology confirmed stage Ia, and no adjuvant treatment was performed. After surgery, considering her history of sequential cancer occurrence, genetic counseling was offered. The result showed the BRCA2 variation of unknown significance mutation. This is the first case report of sequential cancers (endometrial and breast) in a patient with a BRCA2 mutation among a Korean population.

References

May 15, 1997·The New England Journal of Medicine·J P StruewingM A Tucker
Jul 1, 1997·American Journal of Human Genetics·D F EastonD E Goldgar
Mar 27, 2001·Gynecologic Oncology·D A LevineJ Boyd
Apr 15, 2004·JAMA : the Journal of the American Medical Association·Garnet L AndersonUNKNOWN Women's Health Initiative Steering Committee
Jul 5, 2006·British Journal of Cancer·M Vessey, R Painter
Dec 17, 2008·Cancer Control : Journal of the Moffitt Cancer Center·Larissa A MeyerKaren H Lu
Jun 6, 2009·Journal of Cancer Research and Clinical Oncology·Myong Cheol LimSang-Yoon Park
Feb 1, 2013·Oncology·Santhanam ShanmughapriyaKalimuthusamy Natarajaseenivasan

❮ Previous
Next ❯

Citations

Jul 29, 2015·Obstetrics & Gynecology Science·Min Chul ChoiJun Mo Lee
May 13, 2017·Journal of Cellular Biochemistry·Tae-Ho KangJung-Hyun Shim

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
hysterectomy

Related Concepts

Related Feeds

Breast Cancer: BRCA1 & BRCA2

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.