PMID: 7516347Mar 1, 1994Paper

Endometrial endothelial cell proliferation during the menstrual cycle

Human Reproduction
A M Goodger, P A Rogers

Abstract

Adult endometrium is a tissue in which physiological angiogenesis occurs regularly and provides an accessible source of material for study. Endometrial biopsies and immunohistochemistry were used to test two hypotheses: firstly, that there are peaks of endothelial cell proliferation in human endometrium during the menstrual cycle, and secondly that in-vitro endothelial cell migratory signal production by human endometrium (measured in a previous study) accompanies endothelial cell proliferative activity in vivo. Proliferating cells were identified using anti-proliferating cell nuclear antigen, and endothelial cells were identified using anti-CD34. The method was validated by a smaller, separate study using bromodeoxyuridine incorporation and detection with formalin-fixed biopsies, and comparison with proliferating cell nuclear antigen staining. The main study (n = 50) showed that significant peaks of endometrial endothelial cell proliferation could not be identified, due to the large variability in endothelial cell proliferative activity between individuals at the same stage of the menstrual cycle. Endometrial endothelial cell migratory signal production did not correlate with endothelial cell proliferation (n = 27). Results su...Continue Reading

Citations

Sep 15, 2005·Endocrine Reviews·Henry N JabbourHilary O D Critchley
Apr 25, 2017·Journal of Cellular Biochemistry·Mostafa Peyvandi KarizbodaghHamed Mirzaei
Jun 11, 1998·Pediatric Research·A Malamitsi-PuchnerC S Bartsocas
Mar 26, 2002·Climacteric : the Journal of the International Menopause Society·M ReesR Bicknell
Apr 5, 2002·The Journal of Clinical Endocrinology and Metabolism·Nihar R Nayak, Robert M Brenner
Oct 8, 2005·Angiogenesis·Oliver P Milling Smith, Hilary O D Critchley
Jan 1, 1997·American Journal of Reproductive Immunology : AJRI·D S Torry, R J Torry
Apr 29, 2008·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Gui-hua Sha, Shou-qing Lin
Oct 16, 2020·Biochimica Et Biophysica Acta. Reviews on Cancer·Bahar Yetkin-ArikCornelis J F van Noorden
Mar 14, 2002·The American Journal of Pathology·Peter HewettAsif Ahmed
Apr 11, 2001·Trends in Endocrinology and Metabolism : TEM·S K Smith
Jan 6, 2001·Baillière's Best Practice & Research. Clinical Obstetrics & Gynaecology·G Weston, P A Rogers
Jun 3, 2021·Journal of Personalized Medicine·Shiyuan Li, Lijun Ding
Mar 29, 2005·Contraception·Andrew M SharkeyStephen K Smith
Jul 13, 2005·Fertility and Sterility·Pedro XavierJosé Martinez-de-Oliveira
Dec 20, 2005·Fertility and Sterility·Po Mui Lam, Christopher Haines
Jan 14, 2010·The Journal of Steroid Biochemistry and Molecular Biology·Anne E King, Hilary O D Critchley

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.