Endometrioid Adenocarcinoma With Solitary Metastasis to the Appendix, Mimicking Primary Appendiceal Adenocarcinoma: A Case Report and Literature Review

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
Qiujie Ma, Jianshe Wu

Abstract

Metastatic tumors of the appendix are rare. Endometrial cancer tends to metastasize by directly invading neighboring structures; the lung, liver, bones, and brain are common sites of distant metastasis. Herein, we present a case of a solitary endometrial metastatic tumor in the appendiceal mucosa without serosal involvement that mimicked a primary adenocarcinoma of the appendix. The patient who had undergone a radical hysterectomy for an endometrioid adenocarcinoma 3 years earlier presented to the hospital with a history of persistent right-lower abdominal pain. Physical examination showed tension of the abdominal muscles, tenderness, and rebounding pain on the McBurney's point. Open appendectomy for suspected appendicitis revealed a perforation of the distal appendiceal tip. Opening of the surgical specimen showed a mass that was located in the mucosa of the appendix near the appendicular root and resembled a primary tumor of the appendix. Microscopically, the adenocarcinoma of the appendiceal mucosa showed a transitional relationship with the normal mucosa, involving the submucosa and muscles but not invading the serosa. Based on the patient's medical history and the results of immunohistochemical staining, we made a diagnosi...Continue Reading

References

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Oct 3, 2017·Archives of Pathology & Laboratory Medicine·Kyra B Berg, David F Schaeffer

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Citations

Sep 11, 2020·Case Reports in Pathology·Numbereye NumbereAaron R Huber

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Methods Mentioned

BETA
hysterectomy

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