PMID: 11897911Mar 19, 2002Paper

Endometriosis and infertility: the debate continues

Human Fertility : Journal of the British Fertility Society
Johanna Trinder, D J Cahill

Abstract

A causal relationship between minor endometriosis and infertility or subfertility has not yet been demonstrated, although a significant association is shown by prevalence studies. This article critically reviews the evidence for pituitary-ovarian dysfunction as a cause for subfertility in women with minor endometriosis. The lack of fertile controls with endometriosis presents a methodological problem. Group comparison in studies using tubal infertility cases as controls has demonstrated impaired follicular growth, reduced circulating oestradiol concentrations during the preovulatory phase and oestradiol and progesterone during the early luteal phase, and disturbed luteinizing hormone (LH) surge patterns. LH concentration in preovulatory follicular fluid is also reduced, and granulosa cells collected at the same time have impaired steroidogenic capacity in vitro. However, these findings are not consistent in published studies. Significantly lower oocyte fertilization rates (49%) are found compared with controls (69%), even after maximum stimulation with exogenous follicle-stimulating hormone and human chorionic gonadotrophin (52% versus 69%). The implantation rate is also lower (11% versus 13%). An inherent disorder of follicula...Continue Reading

References

Mar 1, 1992·Human Reproduction·A AudebertL Mettler
May 1, 1992·Human Reproduction·P VercelliniP G Crosignani
Jun 1, 1991·British Journal of Obstetrics and Gynaecology·T A MahmoodA A Templeton
Aug 1, 1991·Fertility and Sterility·G A DunselmanJ L Evers
Sep 1, 1990·Fertility and Sterility·C L BarrattI D Cooke
Jun 1, 1990·Fertility and Sterility·M NisolleJ Donnez
Dec 1, 1989·Journal of in Vitro Fertilization and Embryo Transfer : IVF·A M DlugiM M Seibel
Apr 1, 1989·British Journal of Obstetrics and Gynaecology·K BancroftM Elstein
Sep 7, 1985·Lancet·J L YovichD L Willcox
Sep 28, 1985·Lancet·R T O'SheaW R Jones
Feb 1, 1986·Lancet·P G WardleA McDermott
Sep 1, 1986·Fertility and Sterility·P L Matson, J L Yovich
Sep 1, 1988·Fertility and Sterility·F J Rodriguez-EscuderoJ A Benito
Jun 1, 1985·British Journal of Obstetrics and Gynaecology·R J Pepperell, J C McBain
Jan 1, 1985·Acta Obstetricia Et Gynecologica Scandinavica·K Swolin, K Skogsberg
Jan 1, 1996·The Journal of Clinical Endocrinology and Metabolism·C R HarlowM G Hull
Mar 1, 1997·Journal of Assisted Reproduction and Genetics·L SungA B Copperman
Feb 3, 1998·Journal of Assisted Reproduction and Genetics·D J CahillM G Hull
Nov 21, 1998·Journal of Assisted Reproduction and Genetics·A BergendalT Hillensjö
Jan 13, 2000·Fertility and Sterility·W M VerpoestM G Hull

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Citations

Feb 3, 2012·Cell and Tissue Research·Julie A W StilleyKathy L Sharpe-Timms
Dec 29, 2012·Journal of Assisted Reproduction and Genetics·Alisa Komsky-ElbazIdo Ben-Ami
Jan 13, 2004·Journal of Assisted Reproduction and Genetics·Jaume OrdiJuan Balasch
Sep 24, 2009·Human Reproduction Update·E Maria C Ohlsson TeagueM Louise Hull
Dec 3, 2008·Expert Opinion on Emerging Drugs·Sun-Wei Guo
May 1, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Fernanda A MafraCaio P Barbosa
Aug 2, 2008·Fertility and Sterility·Sajal GuptaAshok Agarwal
Apr 12, 2013·Molecular Reproduction and Development·Edson Guimarães Lo TurcoAgnaldo Pereira Cedenho
May 13, 2015·Reproductive Sciences·Lynnette A RuizIdhaliz Flores
May 15, 2007·Current Opinion in Obstetrics & Gynecology·Erol TavmergenEge Nazan Tavmergen Goker

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