Endomyocardial biopsy-integrating electrode at the bioptome tip

Therapeutic Advances in Cardiovascular Disease
Tomas KonecnySamuel Asirvatham

Abstract

The addition of electroanatomic mapping to a standard echo-guided endomyocardial biopsy could identify areas of abnormal pathology and increase the diagnostic yield of the procedure. In this demonstration of a novel technique, a 45-year-old woman with clinical suspicion for cardiac sarcoidosis underwent right ventricular bipolar electroanatomical mapping with identification of areas of signal fractionation and low voltage. A bioptome, configured to record an electrogram from the tip, was then visualized on the three-dimensional electroanatomic mapping (3DEAM) system, and directed to these areas. The biopsy was assisted by the use of a steerable introducer sheath, and by recording unipolar and extended bipolar signals from the bioptome tip. A prominent change in the signal was detected by the electrode at the bioptome tip when the jaws closed on the endomyocardial tissue. Patient tolerated the procedure without complications, and the biopsied samples were appropriate for pathological analysis. Using existing technology, the 3DEAM, which integrates unipolar and bipolar signal from the bioptome tip, is feasible, and can be safely added to a standard echocardiographically guided endomyocardial biopsy. Future studies should investig...Continue Reading

Citations

May 24, 2019·Circulation Research·Carsten TschöpeSophie Van Linthout
Jul 14, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Vaibhav R VaidyaAbhishek J Deshmukh
Oct 14, 2020·Nature Reviews. Cardiology·Carsten TschöpeSophie Van Linthout

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biopsy
sedation
biopsies

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