PMID: 2499536Jan 1, 1989Paper

Endomysial antibodies in the diagnosis of celiac disease and the effect of gluten on antibody titers

Immunological Investigations
V J KumarT Rossi

Abstract

Celiac disease, a common chronic gastrointestinal disorder, is gluten induced and is controlled with a gluten-free diet. While the management of CD with a gluten-free diet is quite effective, the diagnosis is rather difficult. The ESPGAN criteria for the diagnosis of CD seems to be tedious and time-consuming. Serological tests for IgA class endomysial antibodies, as detected by indirect immunofluorescence, on human and primate smooth muscles are specific and sensitive markers of celiac disease. Of all the specimens examined, endomysial antibodies were present in patients with gluten-sensitive enteropathy. These antibodies occurred in all active cases of celiac disease, in 90 percent suspected celiac patients where all the ESPGAN criteria has not been fulfilled. This contrasts to the presence of endomysial antibodies in 46 percent of confirmed and 17 percent of suspected celiac patients maintained on a gluten-free diet for various time intervals. Endomysial antibodies also occurred in all cases with chronic diarrhea and gut histology consistent with CD and 8% of asymptomatic family members of CD patients. None of the patients with other gastrointestinal and liver diseases had endomysial antibodies. These studies thus emphasize t...Continue Reading

References

Feb 27, 1988·Lancet·M MäkiJ K Visakorpi
Jul 1, 1987·Journal of Pediatric Gastroenterology and Nutrition·A KapuscinskaT Rossi
Apr 1, 1986·Archives of Dermatology·P AccettaF Helm
Jun 1, 1987·Digestive Diseases and Sciences·A KeshavarzianP E Isaacs
Oct 1, 1984·The British Journal of Dermatology·T P ChorzelskiA Kapuscinska
Jan 1, 1983·Annals of the New York Academy of Sciences·T P ChorzelskiV Kumar
May 1, 1981·The Journal of Pediatrics·E Lebenthal, D Branski

❮ Previous
Next ❯

Citations

Jan 1, 1982·Archives of Dermatological Research·J ViacJ Thivolet
Dec 12, 1991·The New England Journal of Medicine·J S Trier
Nov 30, 2005·The Proceedings of the Nutrition Society·Norma McGough, John H Cummings
May 26, 1999·Australian and New Zealand Journal of Medicine·A MillerA d'Apice
Jul 25, 2000·Postgraduate Medical Journal·M W James, B B Scott
Aug 9, 2003·Lancet·Peter H R Green, Bana Jabri
Mar 1, 1994·The American Journal of the Medical Sciences·J P Michalski, C C McCombs
Jun 1, 1994·The American Journal of the Medical Sciences·J Wortsman, V Kumar
Aug 18, 2012·Gastrointestinal Endoscopy·Lucinda A HarrisDora Lam-Himlin
May 16, 2009·Seminars in Immunology·Graham A Heap, David A van Heel
Jan 1, 1990·Journal of the American Academy of Dermatology·E H Beutner
Jul 1, 1993·Current Problems in Pediatrics·A W Burks, H Sampson
Jul 1, 1991·Clinics in Dermatology·E H BeutnerV Kumar
Jun 18, 2003·The American Journal of Gastroenterology·Kouroche VahediClaude Matuchansky
Mar 31, 2001·The American Journal of Gastroenterology·A Dahele, S Ghosh
Oct 19, 2002·The American Journal of Gastroenterology·Raanan ShamirRami Eliakim
Feb 24, 2001·The American Journal of Gastroenterology·K J MatherD A Hanley
Mar 3, 2011·The American Journal of Gastroenterology·Kent D KatzJoseph A Murray
Aug 1, 1993·Scandinavian Journal of Gastroenterology·A CarroccioA Notarbartolo
Aug 14, 1998·Journal of Pediatric Gastroenterology and Nutrition·M A Del RosarioS K Gupta
Mar 3, 1998·Journal of Pediatric Gastroenterology and Nutrition·T M Rossi, A Tjota
Nov 1, 1996·Journal of Pediatric Gastroenterology and Nutrition·C Rittmeyer, J M Rhoads
Jun 28, 2001·Clinical and Diagnostic Laboratory Immunology·V KumarJ Wortsman
Oct 25, 2000·Pediatric Research·A PicarelliM C Anania
Sep 1, 1995·Clinical and Experimental Immunology·N LahatA Lerner
Sep 1, 1994·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·A FoisV Di Marco
Feb 10, 2021·The American Journal of Gastroenterology·Melis G CeldirJoseph A Murray
Oct 3, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Melis G CeldirJoseph A Murray

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinica Chimica Acta; International Journal of Clinical Chemistry
A ElewautM H De Baets
Transactions of the Royal Society of Tropical Medicine and Hygiene
F LotheR A Tozer
© 2022 Meta ULC. All rights reserved