Endophytic lesions: a predictor of failure in laparoscopic renal cryoablation

Journal of Endourology
Andrew D WrightKent T Perry

Abstract

Laparoscopic renal cryoablation is an emerging minimally invasive management option for T(1) renal lesions. In an analysis of patients treated with laparoscopic cryoablation for renal lesions, our objective was to compare the treatment outcomes in patients with exophytic/partially exophytic and endophytic (peripheral but completely intrarenal) lesions. We retrospectively reviewed medical records of 32 consecutive patients with anterior renal lesions who were treated with laparoscopic renal cryoablation between 2003 and 2005. Biopsy samples were obtained from the majority of lesions intraoperatively. The lesions were managed with 17 gauge needles and two freeze/thaw cycles. Follow-up was performed with CT scans at 3, 6, and 12 months, and then yearly. Treatment failures were defined as continued enhancement on CT or growth of the lesion. Statistical analysis was performed using t-test, correlative, and multiple regression analysis. A total of 35 lesions in 32 patients were identified. Median lesion size was 1.9 cm. Median age was 67 years, with most patients having significant comorbidities. The median preoperative and postoperative creatinine level was 1.3 and 1.5 mg/dL (P = 0.38). Of the biopsy samples from 27 of 35 lesions, 1...Continue Reading

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Citations

Jan 15, 2011·Journal of Endourology·Joseph A GraversenJaime Landman
Nov 11, 2011·Journal of Endourology·Matvey TsivianThomas J Polascik
Aug 19, 2009·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Young Hwii KoJun Cheon
Jul 16, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Brian C Allen, Erick M Remer
Jan 15, 2010·International Journal of Urology : Official Journal of the Japanese Urological Association·Masaki KimuraThomas J Polascik
Dec 19, 2009·Urology·Timothy R YoostStephen J Savage
Jul 7, 2012·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Marcos F Dall'OglioMiguel Srougi
Aug 28, 2016·Technology in Cancer Research & Treatment·Lasse L NonboeMichael Borre
Dec 17, 2014·Korean journal of urology·Seok Cho, Seok Ho Kang
Apr 24, 2010·Korean journal of urology·Byeong Kuk HamJun Cheon

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