Endorectal diffusion-weighted imaging in prostate cancer to differentiate malignant and benign peripheral zone tissue

Journal of Magnetic Resonance Imaging : JMRI
Keyanoosh Hosseinzadeh, Samuel David Schwarz

Abstract

To determine if the apparent diffusion coefficient (ADC) can discriminate benign from malignant peripheral zone (PZ) tissue in patients with biopsy-proven prostate cancer that have undergone endorectal diffusion-weighted imaging (DWI) of the prostate. Ten patients with prostate cancer underwent endorectal magnetic resonance imaging (MRI) in addition to DWI. A two-dimensional grid was placed over the axial images, and each voxel was graded by a 4-point rating scale to discriminate nonmalignant from malignant PZ tissue based on MR images alone. ADC was then determined for each voxel and plotted for nonmalignant and malignant voxels for the entire patient set. Second, with the radiologist aware of biopsy locations, any previously assigned voxel grade that was inconsistent with biopsy data was regrouped and ADCs were replotted. For the entire patient set, without and with knowledge of the biopsy data, the mean ADCs for nonmalignant and malignant tissue were 1.61 +/- 0.27 and 1.34 +/- 0.38 x 10(-3) mm2/second (P = 0.002) and 1.61 +/- 0.26 and 1.27 +/- 0.37 x 10(-3) mm2/second (P = 0.0005), respectively. DWI of the prostate is possible with an endorectal coil. The mean ADC for malignant PZ tissue is less than nonmalignant tissue, alt...Continue Reading

Associated Clinical Trials

Oct 20, 2015·Lawrence Schwartz

References

Mar 1, 1986·AJR. American Journal of Roentgenology·P J BryanJ R Haaga
Jan 1, 1985·Radiology·P Y PoonA W Bruce
Aug 1, 1989·Radiology·M D SchnallH Y Kressel
Jul 1, 1993·AJR. American Journal of Roentgenology·F G SommerR N Low
Apr 1, 1996·AJR. American Journal of Roentgenology·G J JagerJ O Barentsz
Apr 1, 1996·NMR in Biomedicine·G P LineyA Horsman
Jun 18, 1999·Journal of Magnetic Resonance Imaging : JMRI·T NamimotoM Takahashi
Feb 9, 2000·Radiologic Clinics of North America·G D Grossfeld, F V Coakley
Feb 9, 2000·Radiologic Clinics of North America·K K Yu, H Hricak
Feb 9, 2000·Radiologic Clinics of North America·J KurhanewiczH Hricak
Dec 6, 2000·Journal of Magnetic Resonance Imaging : JMRI·T Moteki, H Ishizaka
Jul 4, 2001·Journal of Magnetic Resonance Imaging : JMRI·M RiesN Grenier
Dec 18, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P GibbsL W Turnbull
Aug 31, 2002·Journal of Magnetic Resonance Imaging : JMRI·Yong GuoJia-Hong Gao
Sep 28, 2002·Journal of Magnetic Resonance Imaging : JMRI·John KurhanewiczDaniel B Vigneron

❮ Previous
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Citations

Oct 14, 2011·Abdominal Imaging·Nelly TanSteven S Raman
Oct 8, 2008·European Radiology·Tomohiro NamimotoYasuyuki Yamashita
Oct 12, 2010·European Radiology·Cher Heng TanVikas Kundra
Sep 17, 2008·Magma·Yousef MazaheriHedvig Hricak
Aug 27, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·J KhalifaR de Crevoisier
Jan 24, 2006·Investigative Radiology·Peter GibbsLindsay W Turnbull
May 18, 2007·Investigative Radiology·Guglielmo ManentiGiovanni Simonetti
Oct 9, 2007·The Cancer Journal·Nicholas J van As, Chris C Parker
Apr 2, 2008·Journal of Computer Assisted Tomography·Chan Kyo Kim, Byung Kwan Park
Mar 18, 2011·Journal of Computer Assisted Tomography·Jin YamamuraUlrike Wedegaertner
Mar 16, 2013·Journal of Computer Assisted Tomography·Guanqiao JinXiang Yang Huang
Aug 21, 2009·Investigative Radiology·Peter GibbsLindsay W Turnbull
Jun 11, 2009·Topics in Magnetic Resonance Imaging : TMRI·Michael A JacobsKatarzyna J Macura
Oct 4, 2006·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Elizabeth M Charles-Edwards, Nandita M deSouza
Oct 1, 2010·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·G Petralia, H C Thoeny
Jan 5, 2012·Advances in Urology·Rajakumar NagarajanM Albert Thomas
Aug 9, 2013·BMC Medical Imaging·Alexander WongMasoom Haider
Dec 21, 2006·AJR. American Journal of Roentgenology·Stefan A ReinsbergNandita M deSouza
Jul 25, 2007·AJR. American Journal of Roentgenology·Masoom A HaiderJohn Trachtenberg
Nov 26, 2009·AJR. American Journal of Roentgenology·Sophie F RichesNandita M deSouza
May 22, 2009·AJR. American Journal of Roentgenology·Gary J KelloffUNKNOWN Prostate Cancer Imaging Working Group
May 22, 2010·AJR. American Journal of Roentgenology·Chan Kyo KimBohyun Kim
Mar 5, 2011·AJR. American Journal of Roentgenology·Sadhna Verma, Arumugam Rajesh
Sep 22, 2012·AJR. American Journal of Roentgenology·Hiroshi ShinmotoRobert V Mulkern
Mar 17, 2009·Future Oncology·Christina Messiou, Nandita M deSouza
Mar 28, 2012·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Shinji YamazoeKunihiko Fukuda
Feb 2, 2008·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Dow-Mu KohDavid J Collins
Jul 8, 2008·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Kazuhiro KitajimaKazuro Sugimura
Mar 25, 2011·The Indian Journal of Radiology & Imaging·Paramjeet SinghNiranjan Khandelwal

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