Endorectal MR imaging and MR spectroscopic imaging for locally recurrent prostate cancer after external beam radiation therapy: preliminary experience

Radiology
Fergus V CoakleyJohn Kurhanewicz

Abstract

To evaluate endorectal magnetic resonance (MR) imaging and MR spectroscopic imaging for the depiction of locally recurrent prostate cancer after external beam radiation therapy. Endorectal MR imaging and MR spectroscopic imaging were performed in 21 patients with biochemical failure after external beam radiation therapy for prostate cancer. Two readers independently and retrospectively reviewed MR images and rated the likelihood of recurrent tumor on a five-point scale. Spectroscopic voxels were considered suspicious for malignancy if the choline level was elevated and citrate was absent. Receiver operating characteristic curve analysis was used to assess cancer detection in each side of the prostate with endorectal MR imaging and spectroscopic imaging at different thresholds based on the scores assigned by the two readers and on the number of suspicious voxels in each hemiprostate, respectively. The presence or absence of cancer at subsequent transrectal biopsy was used as the standard of reference. Biopsy demonstrated locally recurrent prostate cancer in nine hemiprostates in six patients. The area under the receiver operating characteristic curve for the detection of locally recurrent cancer with MR imaging was 0.49 and 0.51...Continue Reading

References

Sep 1, 1991·Journal of Magnetic Resonance Imaging : JMRI·T W Chan, H Y Kressel
Jan 1, 1988·Statistics in Medicine·J R LandisG G Koch
Sep 1, 1982·The American Journal of Surgical Pathology·D G BostwickL F Fajardo
Mar 1, 1997·Urology·P R CarrollM Roach
Aug 1, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J Star-LackD B Vigneron
Jan 13, 1999·International Journal of Impotence Research·F M JhaveriC C Carson
Sep 7, 2000·International Journal of Radiation Oncology, Biology, Physics·J CrookM Abdolell
May 31, 2001·International Journal of Radiation Oncology, Biology, Physics·C MenardT Bezabeh
Jul 10, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·U G Mueller-LisseJ Kurhanewicz
Sep 28, 2002·Journal of Magnetic Resonance Imaging : JMRI·John KurhanewiczDaniel B Vigneron
Dec 24, 2002·Prostate Cancer and Prostatic Diseases·J L Letran, M K Brawer
Oct 13, 2006·Current Opinion in Urology·F Parivar, J Kurhanewicz

❮ Previous
Next ❯

Citations

Feb 22, 2012·Der Radiologe·A M WeidnerS O Schoenberg
Jun 22, 2006·Der Urologe. Ausg. A·N Morakkabati-SpitzS C Müller
Sep 29, 2006·Der Urologe. Ausg. A·S N ReskeG Glatting
Mar 14, 2013·Der Urologe. Ausg. A·A KretschmerD Tilki
Jul 13, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Susanne AlbrechtRaymond Miralbell
Sep 25, 2007·European Journal of Nuclear Medicine and Molecular Imaging·B J KrauseM Schwaiger
Nov 16, 2012·European Journal of Nuclear Medicine and Molecular Imaging·Francesco CeciStefano Fanti
Sep 7, 2006·Abdominal Imaging·Emanuele Casciani, Gian Franco Gualdi
May 4, 2007·Abdominal Imaging·Joan C Vilanova, Joaquim Barceló
Apr 23, 2013·Abdominal Imaging·P J L De VisschereG M Villeirs
Nov 19, 2009·European Radiology·Olivier RouvièreDenis Lyonnet
Feb 11, 2012·European Radiology·Jelle O BarentszUNKNOWN European Society of Urogenital Radiology
Sep 17, 2008·Magma·Yousef MazaheriHedvig Hricak
Jun 23, 2009·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·José A RichterMaría J García-Velloso
Apr 25, 2006·Current Urology Reports·Edouard J TrabulsiLeonard G Gomella
Feb 14, 2006·Nature Clinical Practice. Urology·Renata HuzjanHedvig Hricak
Feb 14, 2006·Nature Clinical Practice. Urology·Anwar R PadhaniDavid O Cosgrove
Jan 5, 2012·Advances in Urology·Rajakumar NagarajanM Albert Thomas
Apr 24, 2008·AJR. American Journal of Roentgenology·Emanuele CascianiGian Franco Gualdi
May 22, 2009·AJR. American Journal of Roentgenology·Gary J KelloffUNKNOWN Prostate Cancer Imaging Working Group
May 22, 2010·AJR. American Journal of Roentgenology·Pieter J De VisschereGeert M Villeirs
Oct 24, 2006·Pharmacogenomics·Kristine Glunde, Natalie J Serkova
Jan 20, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Young Jun ChoiKyoung-Sik Cho
May 18, 2010·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·P PaparelUNKNOWN membres du sous-comité prostate du CCAFU

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.