Endoscopic and Clinical Factors Affecting the Prognosis of Colorectal Endoscopic Submucosal Dissection-Related Perforation

Gut and Liver
Dong-Uk KangJeong-Sik Byeon

Abstract

Although colorectal endoscopic submucosal dissection (ESD)-related perforation is not uncommon, the factors affecting clinical outcomes after perforation have not been investigated. This study was designed to investigate the factors influencing the clinical course of ESD-related colon perforation. Forty-three patients with colorectal ESD-related perforation were evaluated. The perforations were classified as endoscopic or radiologic perforations. The patients' medical records and endoscopic pictures were analyzed. The clinical outcomes were assessed by the duration of nil per os, intravenous antibiotics administration, and hospital stays, which were 2.7±1.5, 4.9±2.3, and 5.1±2.3 days, respectively. Multivariate analyses revealed that a larger tumor size, ESD failure, specific endoscopists, and abdominal pain were independently related to a poorer outcome. The time between perforation and clipping was 15.8±25.4 minutes in the endoscopic perforation group. The multivariate analysis of this group indicated that delayed clipping, specific endoscopists, and abdominal pain were independently associated with poorer outcomes. Tumor size, ESD failure, abdominal pain, and the endoscopist were factors that affected the clinical outcomes o...Continue Reading

References

Jun 4, 2005·Endoscopy·UNKNOWN Endoscopic Classification Review Group
Jun 27, 2007·Gastrointestinal Endoscopy·Shinji TanakaKazuaki Chayama
Apr 10, 2010·World Journal of Gastroenterology : WJG·Naohisa YoshidaToshikazu Yoshikawa
Jul 2, 2010·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Shinji TanakaHiro-O Yamano
Jun 15, 2011·Gastrointestinal Endoscopy·Jeong-Sik ByeonJin-Ho Kim
Aug 30, 2014·Gut and Liver·Sang Pyo LeeChan Sup Shim

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Methods Mentioned

BETA
dissection
X-ray

Software Mentioned

SPSS

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