Endoscopic and histological features of gastric cancers after successful Helicobacter pylori eradication therapy

Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Akiko SakaSatoshi Nimura

Abstract

Gastric cancer after successful Helicobacter pylori eradication therapy is often difficult to diagnose by endoscopy because of its indistinct borderline or lack of obviously cancerous characteristics. Furthermore, it has become evident that non-neoplastic epithelium covers cancerous areas in gastric cancer after eradication. Here, we investigated these endoscopic features and their relationship to histological findings. We studied 24 and 47 gastric cancers in patients who had (eradication group) and had not (control group) undergone H. pylori eradication, respectively. A gastritis-like appearance revealed by conventional endoscopy was defined as a mucosal pattern with no marked difference from the surrounding non-cancerous area and that revealed by narrow-band imaging (NBI)-magnifying endoscopy (ME) as the mucosal pattern observed in H. pylori-associated atrophic gastritis. We investigated a gastritis-like appearance revealed by conventional endoscopy (A), a gastritis-like appearance at the margin (B) and within (C) the cancerous area revealed by NBI-ME, and the histological characteristics of the overlying non-neoplastic epithelium. We also evaluated the relationship between endoscopic and histological findings in the eradicat...Continue Reading

References

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Mar 11, 2015·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Akiko SakaSatoshi Nimura

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Citations

Oct 2, 2015·Digestive Diseases and Sciences·Kazutoshi HoriHiroto Miwa
May 24, 2016·Gastroenterology Research and Practice·Noriyuki HoriguchiNaoki Ohmiya
Aug 5, 2017·International Journal of Molecular Sciences·Tetsuya TsukamotoXueyuan Cao
Dec 23, 2017·Gastroenterology Research and Practice·Kazuhiro MizukamiKazunari Murakami
Nov 6, 2018·Clinical Endoscopy·Hiroyuki OsawaHironori Yamamoto
Jul 22, 2017·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Noriyuki HoriguchiNaoki Ohmiya
Oct 20, 2018·Mini Reviews in Medicinal Chemistry·Armin KhomamiAli Almasirad
Nov 26, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yoshiyasu KitagawaTaketo Yamaguchi
Jul 14, 2016·Expert Opinion on Biological Therapy·Michael Davidson, Ian Chau
Nov 30, 2016·Journal of Clinical Biochemistry and Nutrition·Toshihiro NishizawaOsamu Toyoshima
Oct 6, 2020·Endoscopy International Open·Kohei MatsumotoAkihito Nagahara
Oct 13, 2015·World Journal of Gastroenterology : WJG·Masaaki KobayashiShuji Terai
Jun 10, 2017·Gastroenterology Research and Practice·Yoshikazu YoshifukuKazuaki Chayama
Nov 9, 2019·Therapeutic Advances in Gastroenterology·Satoshi ShinozakiHironori Yamamoto
Mar 11, 2015·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Akiko SakaSatoshi Nimura
Oct 14, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ioana Alexandra CardosSimona Cavalu
Mar 18, 2019·Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology·Mitsuru NakagawaTetsuya Tsukamoto
Nov 18, 2021·Virchows Archiv : an International Journal of Pathology·Kotaro ShibagakiShunji Ishihara

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Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.