PMID: 11336139May 5, 2001Paper

Endoscopic and histopathological evaluation of preschool children with chronic diarrhoea

Journal of Tropical Pediatrics
O P MishraG Nath

Abstract

Fifty-seven children with chronic diarrhoea, aged 1-5 years, were studied. Protein-energy malnutrition was present in 49 (85.9 per cent) children. Anaemia (89.5 per cent), presence of mucus and blood in stool (66.6 per cent), abdominal distension (52.6 per cent), and abdominal pain (28.1 per cent) were the common clinical findings at admission. The enteropathogens isolated from the stool of 68.4 per cent of patients were Escherichia coli (19.3 per cent), Candida albicans (12.3 per cent), E. histolytica (8.8 per cent), and Giardia lamblia (7 per cent). Secondary lactose intolerance was present in 21 per cent of children, endoscopic appearance was abnormal in 23.3 per cent of children and the commonest finding was chronic duodenitis (16.7 per cent). Abnormal histopathology was observed in 73.3 per cent of cases and villous atrophy with mononuclear cell infiltration (56.7 per cent) was the most common abnormality detected. The mean duration of diarrhoea had no impact on endoscopic appearance but it significantly affected the histopathological changes. However, no correlation was found in endoscopic and histopathological lesions in relation to malnutrition and aetiological agents.

Citations

Aug 26, 2014·PloS One·Maren Johanne Heilskov RytterVibeke Brix Christensen
Jul 3, 2013·Journal of Tropical Pediatrics·Ujjal PoddarAnshu Srivastava
Jun 19, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Michaela KerberMaximilian Ledochowski
Jul 29, 2017·Environmental Microbiology·Shafiqul A SarkerHarald Brüssow
Jan 27, 2006·World Journal of Gastroenterology : WJG·Thanaa Ea HelalOsama Abo El Fotoh
Jan 1, 2021·Histopathology·Nicole C Panarelli

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