Endoscopic biopsies from normal-appearing terminal ileum and cecum in patients with suspected colonic tuberculosis

Endoscopy
S P MisraB K Kunwar

Abstract

Colonic tuberculosis is generally diagnosed by colonoscopy and targeted biopsy of lesions. However, the diagnostic yield of colonic biopsies is not very good. So far as we are aware, there have been no studies investigating the role of biopsies from endoscopically normal-appearing cecum and terminal ileum in diagnosing colonic or ileal tuberculosis, or both. Patients with a clinical suspicion of colonic tuberculosis, in whom no endoscopic abnormalities were found on colonoscopy or ileoscopy, were included in the study. Multiple biopsies were obtained from the cecum and ileum. Fifty patients were studied. Intubation of the terminal ileum was possible in 43 patients (86 %). Histological examination of biopsies obtained from the cecum and terminal ileum showed noncaseating granuloma in two patients. Both of these biopsies were from the terminal ileum. In two other patients, collections of loosely arranged epithelioid cells were observed. This established the diagnosis in these four patients (8 %). In the remaining 46 patients, histology showed nonspecific inflammation in 18 patients (in the cecum in 15 and in the terminal ileum in seven). The other biopsies did not show any abnormalities (33 from the cecum, 34 from the terminal il...Continue Reading

Citations

Mar 15, 2006·Digestive Diseases and Sciences·Nicholas A NetherlandMohamad A Eloubeidi
Nov 25, 2005·Alimentary Pharmacology & Therapeutics·R Hinds, K Soondrum
Apr 15, 2015·International Journal of Colorectal Disease·Katsunori SekineNaomi Uemura
Jul 7, 2009·Arquivos De Gastroenterologia·Marcelo Maia Caixeta de MeloJoão Gomes Netinho
Nov 3, 2015·Medwave·Richard Castillo RamosGonzalo Urrejola Schmied
May 24, 2006·World Journal of Gastroenterology : WJG·S-P MisraV Misra
Apr 13, 2006·World Journal of Gastroenterology : WJG·Sri Prakash MisraManisha Dwivedi
Nov 17, 2010·Revista do Colégio Brasileiro de Cirurgiões·Marcelo Maia Caixeta de Melo, João Gomes Netinho

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