Endoscopic findings in the upper gastrointestinal tract of faecal occult blood-positive, colonoscopy-negative patients

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
K HisamuddinP S Phull

Abstract

Detection of faecal occult blood is recommended for colorectal cancer screening in average risk populations. However, many subjects do not have any cause found in the colon to account for the occult blood loss. To determine the prevalence of upper gastrointestinal tract disease in faecal occult blood-positive, colonoscopy-negative patients. Retrospective audit of 99 patients (56 females; mean age 60 years, range 18-83) who underwent same-day colonoscopy and upper gastrointestinal endoscopy over a 2-year period. Fifty-two of the 99 patients had a normal colonoscopy, 16 had diverticulosis and 2 had hyperplastic polyps; these 70 patients comprised the colonoscopy-negative group. Significant upper gastrointestinal tract disease was noted in 25 (36%) of the colonoscopy-negative group compared with 10 (34%) of the 29 colonoscopy-positive group (p=ns). Most of the upper gastrointestinal tract lesions identified were benign. Within the colonoscopy-negative group, patients with anaemia or upper gastrointestinal tract symptoms had a higher prevalence of positive findings in the upper gastrointestinal tract, but this association was not statistically significant. Endoscopic examination of the upper gastrointestinal tract in faecal occult ...Continue Reading

Citations

Sep 29, 2011·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Lukejohn W DayJohn M Inadomi
Oct 11, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A CarreraR J C Steele
Aug 4, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Tsung-Hsien ChiangMing-Shiang Wu
Oct 22, 2010·European Journal of Gastroenterology & Hepatology·Zohar LeviYaron Niv
Nov 3, 2016·Internal Medicine·Yu HatanoAkiko Shiotani

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