Endoscopic Injection of Low Dose Triamcinolone: A Simple, Minimally Invasive, and Effective Therapy for Interstitial Cystitis With Hunner Lesions

Urology
Michael G FunaroSonia Bahlani

Abstract

To investigate the efficacy of low dose triamcinolone injection for effectiveness and durability in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) with Hunner lesions (HL). Clinical data from patients with HL who underwent endoscopic submucosal injection of triamcinolone were reviewed. Demographics, pre- and postoperative pain and nocturia scores, and long-term clinical outcomes were assessed. Duration of response was estimated by time to repeat procedure. Kaplan-Meier estimator was used to evaluate time to repeat procedure. A total of 36 patients who received injections of triamcinolone between 2011 and 2015 were included. Median age ± standard deviation of patients was 61.5 ± 12.0 years; 28 (77.8%) were female patients and 8 (22.2%) were male patients. Twenty six patients (72.2%) received only 1 set of injections, 8 (22.2%) received 2 sets of injections, and 2 (5.56%) received 3 or more sets of injections. Average time between injections in those receiving more than 1 set of injections was 344.9 days (median: 313.5, range: 77-714). Preprocedural pain scores were 8.3 ± 1.2 (mean ± standard deviation) on Likert pain scale (0-10), and mean postprocedural pain scores at approximately 1 month were 3.8 ± 2.2, P ...Continue Reading

Citations

Apr 5, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Yoshiyuki AkiyamaYukio Homma
Nov 27, 2018·F1000Research·Pradeep TyagiChristopher Chermansky
Apr 16, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Yukio HommaKyu-Sung Lee
Aug 22, 2021·Obstetrics and Gynecology Clinics of North America·Catherine Chandler Moody, Tola B Fashokun
Dec 1, 2021·Aktuelle Urologie·Thomas Bschleipfer, Björn Kaftan

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