Endoscopic Lipofilling for the Treatment of Bronchopleural Fistulas After Anatomic Lung Resection.

The Annals of Thoracic Surgery
Edoardo BottoniMarco Alloisio

Abstract

A bronchopleural fistula is a potentially fatal complication of anatomic lung resection surgery. Bronchoscopy has been described in the treatment of small-caliber fistulas. An endoscopic procedure based on instillation of mesenchymal stem cells for the treatment of bronchopleural fistula has recently been successful. Fat tissue is rich in mesenchymal stem cells, and we describe a technique based on the instillation of autologous fat (lipofilling) for the treatment of bronchopleural fistulas. The procedure was applied to 8 subjects affected by bronchopleural fistulas that were greater than 8 mm in diameter, and saw resolution in all cases.

References

Dec 12, 2002·Molecular Biology of the Cell·Patricia A ZukMarc H Hedrick
Jan 1, 2015·The New England Journal of Medicine·Francesco PetrellaMarika Zanotti
Nov 8, 2017·Seminars in Thoracic and Cardiovascular Surgery·Antonio MazzellaLorenzo Spaggiari
Dec 1, 2017·Annals of Medicine and Surgery·Elisa BelliniEdoardo Raposio

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