Endoscopic Mucosal Resection Performed Underwater for Nonampullary Duodenal Epithelial Tumor: Evaluation of Feasibility and Safety

Gastroenterology Research and Practice
Goro ShibukawaHiroshi Hojo

Abstract

Recently, opportunities to encounter superficial nonampullary duodenal epithelial tumor (SNADET) have increased. EMR and ESD are performed to treat SNADET. However, the rate of perforation is higher than that of other gastrointestinal lesions, regardless of which method is used. Underwater EMR (UW-EMR) is immersion treatment of SNADET, which has low risk of perforation and can remove lesions safely and completely. In the present study, we retrospectively investigated patients in whom UW-EMR was performed to evaluate the feasibility and safety of UW-EMR for the treatment of SNADET. The primary endpoint was to evaluate the feasibility of UW-EMR for the treatment of SNADET, and secondary objective was to determine the operation's safety. There were 14 participants, with a total of 16 lesions, who underwent UW-EMR between August 2015 and December 2017. Histological heteromorphism revealed that seven patients had low-grade adenoma, seven had high-grade adenoma, and two had adenocarcinoma. En bloc resection was performed in 14 lesions. In two patients, nodular lesions were observed in the scar and biopsy confirmed recurrences. There were no serious adverse events including bleeding or perforation. UW-EMR may be a safe and effective t...Continue Reading

References

Aug 1, 1996·International Journal of Epidemiology·J S ChowA I Neugut
Dec 10, 2008·Annals of Epidemiology·David SchottenfeldFawn D Vigneau
Dec 9, 2010·The American Journal of Gastroenterology·Kazuhisa OkadaMasahiro Igarashi
Mar 1, 2012·Gastrointestinal Endoscopy·Kenneth F BinmoellerSteve Kane
May 7, 2013·Gastrointestinal Endoscopy·Kenneth F BinmoellerSteve D Kane
Apr 23, 2014·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Kenichi GodaNoritsugu Abe
May 20, 2015·World Journal of Gastroenterology : WJG·Naomi KakushimaHiroyuki Ono

❮ Previous
Next ❯

Citations

Sep 10, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yoshiyuki KiguchiNaohisa Yahagi
May 18, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yorimasa YamamotoHaruhiro Inoue
Aug 11, 2020·World Journal of Clinical Cases·Dong Hyun KimSung Kyu Choi
Mar 19, 2021·Scandinavian Journal of Gastroenterology·Yi Fang, Xiaoyun Ding
Apr 27, 2021·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Hyo-Joon Yang
Jul 29, 2021·Journal of Gastroenterology and Hepatology·Yosuke ToyaTakayuki Matsumoto

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
sedation
biopsy
surgical resection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.