Endoscopic papillary balloon dilation causes transient pancreatobiliary and duodenobiliary reflux

Gastrointestinal Endoscopy
Masanori Sugiyama, Yutaka Atomi

Abstract

Endoscopic papillary balloon dilation reduces sphincter function at least transiently or partially, which may allow pancreatobiliary and duodenobiliary reflux to occur. This study prospectively evaluated pancreatobiliary and duodenobiliary reflux after endoscopic papillary balloon dilation. In 12 patients with choledocholithiasis, ductal bile was sampled for amylase concentration and bacterial culture during ERCP, before and at 7 days to 5 years after endoscopic papillary balloon dilation. To provide comparative and control data, ductal bile was sampled in 12 patients with gallbladder cholesterol polyps and 6 with anomalous pancreaticobiliary junction who did not undergo endoscopic papillary balloon dilation. Amylase concentrations in ductal bile from patients with choledocholithiasis before endoscopic papillary balloon dilation were marginally significantly higher (before Bonferroni correction) compared with concentrations in bile from patients with gallbladder polyps. The concentration of amylase in bile was significantly increased at 7 days after endoscopic papillary balloon dilation compared with that before endoscopic papillary balloon dilation; the level was comparable with that of patients with an anomalous pancreaticobi...Continue Reading

References

Mar 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K ShimadaF Nakayama
Nov 1, 1993·Gastrointestinal Endoscopy·G R MayW Chong
Mar 23, 1999·The American Journal of Gastroenterology·M Sugiyama, Y Atomi
Apr 1, 2003·Gastrointestinal Endoscopy·Masanori SugiyamaYutaka Atomi

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Citations

Feb 11, 2011·Journal of Gastroenterology and Hepatology·Shaolong SunShupeng Yu
Nov 27, 2008·World Journal of Gastroenterology : WJG·Terumi KamisawaKouji Tsuruta
May 15, 2010·Journal of Gastroenterology·Takeshi TsujinoKazuhiko Koike
Jun 6, 2013·Journal of Gastroenterology·Jun HoraguchiUNKNOWN committee of Diagnostic Criteria of The Japanese Study Group on Pancreaticobiliary Maljunction
Apr 3, 2007·Gastrointestinal Endoscopy Clinics of North America·Jeremy S Rochester, David L Jaffe
Apr 16, 2010·Journal of Hepato-biliary-pancreatic Sciences·Terumi KamisawaUNKNOWN Committee of Diagnostic Criteria of The Japanese Study Group on Pancreaticobiliary
Jan 22, 2019·European Journal of Gastroenterology & Hepatology·Masaaki NatsuiToshifumi Sato
Oct 7, 2010·Journal of Hepato-biliary-pancreatic Sciences·Noritoshi KobayashiItaru Endo
Jul 7, 2011·European Journal of Gastroenterology & Hepatology·Masaaki NatsuiHiroto Nakadaira
Apr 25, 2013·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Masaaki NatsuiHiroto Nakadaira
Jun 30, 2021·Clinical Nuclear Medicine·Meixin Zhao, Weifang Zhang

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