Endoscopic papillectomy of benign ampullary lesions: Outcomes from a multicenter study

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology
Tan AttilaBülent Ödemiş

Abstract

Endoscopic papillectomy (EP) has emerged as an alternative to surgery in the management of ampullary lesions. The aim of this study is to evaluate feasibility, efficacy, safety, outcome, and impact of EP in the management of benign ampullary lesions. This is a multicenter, retrospective study of 44 patients who had EP of benign ampullary lesions. Over the 11-year period, 44 (55.7%) of 79 patients underwent EP for benign ampullary lesions. Complete resection was achieved in 40 patients (91%). An underlying adenocarcinoma was the only risk factor for incomplete resection. Twenty-eight lesions (63.6%) were resected en-bloc and 16 lesions (36.4%) were resected in piecemeal fashion. Post-papillectomy histopathologic diagnoses were tubular adenoma in 14 patients (32%), invasive adenocarcinoma in 9 patients (20.5%), tubullovillous adenoma in 7 patients (16%), tubullovillous adenoma with carcinoma limited to the mucosal layer in 5 patients (11.3%), adenoma with high-grade dysplasia in 4 patients (9%), neuroendocrine tumor in 1 patient (2.3%), ganglioneuroma in 1 patient (2.3%), hamartomatous polyp in 1 patient (2.3%), adenofibroma in 1 patients (2.3%), and Brunner gland hyperplasia in 1 patient (2.3%). Seven (15.9%) procedure-related c...Continue Reading

Citations

May 10, 2020·Expert Review of Gastroenterology & Hepatology·Kenjiro YamamotoTakao Itoi
Mar 10, 2020·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Bülent ÖdemişMustafa Cengiz
Aug 3, 2020·Current Opinion in Gastroenterology·Jagpal S KlairRichard Kozarek
Apr 13, 2019·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Kwun Wah WenWon-Tak Choi
Aug 21, 2020·Clinical Journal of Gastroenterology·Yasutoshi ShiratoriKatsuyuki Fukuda
Nov 13, 2020·World Journal of Gastroenterology : WJG·Lei JiangHong-Bin Wang
Dec 4, 2020·World Journal of Gastrointestinal Endoscopy·Andrew ChanRajvinder Singh

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