Endoscopic resection of advanced ampullary adenomas: a single-center 14-year retrospective cohort study.

Surgical Endoscopy
Sophia E van der WielMarco J Bruno

Abstract

Endoscopic ampullectomy has been recognized as a safe and reliable means to resect selective tumors of the ampulla of Vater and is associated with lower morbidity and mortality rates compared to surgical resection. Success rates range from 42 to 92%, with recurrences reported in up to 33%. Studies on endoscopic resection of advanced lesions such as those with intraductal extension of adenoma (IEA) and lateral spreading adenomas (LSA) are limited. We aimed to evaluate the technical success, complications, and recurrence of endoscopic resection of ampullary adenomas, including advanced lesions. All patients referred to the Erasmus Medical Center for endoscopic resection of an ampullary lesion were retrospectively identified between 2002 and 2016. Endoscopic success was defined as complete excision of the adenoma, irrespective of the number of attempts, in the absence of recurrence. We included 87 patients with a median age of 65 years. Of these, 56 patients (64%) had an adenoma confined to the ampulla (ACA), 20 patients (23%) had an LSA, and 11 patients (13%) were treated for an IEA. The median lesion sizes were 24.6 mm, 41.4 mm, and 16.3 mm, respectively (P < 0.001). Complications occurred in 22 patients (25.3%), of which hemorr...Continue Reading

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Citations

Nov 7, 2019·Journal of Gastroenterology and Hepatology·Koichi KagawaAtsushi Nakajima
May 10, 2020·Expert Review of Gastroenterology & Hepatology·Kenjiro YamamotoTakao Itoi
Mar 10, 2020·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Bülent ÖdemişMustafa Cengiz
Apr 13, 2019·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Kwun Wah WenWon-Tak Choi
Feb 8, 2020·Therapeutic Advances in Gastrointestinal Endoscopy·Jan-Werner Poley, Sara Campos
Aug 3, 2020·Current Opinion in Gastroenterology·Jagpal S KlairRichard Kozarek
Dec 4, 2019·Clinical Endoscopy·Ichiro YasudaHaruka Fujinami
Jul 16, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Yoonhyeong ByunJin-Young Jang
Dec 4, 2020·World Journal of Gastrointestinal Endoscopy·Andrew ChanRajvinder Singh
Apr 23, 2021·Gastrointestinal Endoscopy·Jeska A FritzscheRogier P Voermans

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Methods Mentioned

BETA
biopsy
surgical resection

Software Mentioned

ENDOBASE
SPSS

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