Endoscopic Submucosal Dissection for Gastric Subepithelial Tumors: A Single-Center Experience

Gastroenterology Research and Practice
Jin Sung LeeGeun Am Song

Abstract

Background and Aims. Endoscopic submucosal dissection (ESD) has been accepted as a treatment modality for gastrointestinal epithelial tumors. Recently, ESD has been applied to resect subepithelial tumors (SETs) in the gastrointestinal tract, but clinical evidence on its efficacy and safety is limited. The aim of this study was to investigate the efficacy and safety of ESD for gastric SETs and to assess possible predictive factors for incomplete resection. Patients and Methods. Between January 2006 and December 2013, a total of 49 patients with gastric SET underwent ESD at our hospital. Clinicopathologic characteristics of patients and SETs, therapeutic outcomes, complications, and follow-up outcomes were evaluated. Results. The overall rates of en bloc resection and complete resection were 88% (43/49) and 84% (43/49), respectively. Complete resection rates in tumors originating from the submucosal layer were significantly higher than those in tumors originating from the muscularis propria layer (90% versus 56%, P = 0.028). In multivariate logistic regression analyses, tumor location (upper third: odds ratio [OR] 12.639, 95% confidence interval [CI] 1.087-146.996, P = 0.043) and layer of tumor origin (muscularis propria: OR 8.17...Continue Reading

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Citations

Sep 15, 2017·Fukushima Journal of Medical Science·Mizue IchinoseMasayuki Miyata
Nov 28, 2019·Gastroenterology Research and Practice·Yingjie GuoZibin Tian
Jan 14, 2020·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·D M LiY P Jiang

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Methods Mentioned

BETA
biopsy
dissection
sedation
SMA
surgical resection

Software Mentioned

SPSS

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