Endoscopic treatment for gastrointestinal stromal tumor: Advantages and hurdles

World Journal of Gastrointestinal Endoscopy
Hyung Hun Kim

Abstract

One of the most prominent characteristics of gastrointestinal stromal tumors (GISTs) is their unpredictable and variable behavior. GISTs are not classified as "benign" or "malignant" but are rather stratified by their associated clinical risk of malignancy as determined by tumor size, location, and number of mitoses identified during surgical histology. The difficulty in assessing the malignant potential and prognoses of GISTs as well as the increasing incidence of "incidental GISTs" presents challenges to gastroenterologists. Recently, endoscopic enucleation has been actively performed as both a diagnostic and therapeutic intervention for GISTs. Endoscopic enucleation has several advantages, including keeping the stomach intact after the removal of GISTs, a relatively short hospital stay, a conscious sedation procedure, relatively low cost, and fewer human resources required compared with surgery. However, a low complete resection rate and the risk of perforation could reduce the overall advantages of this procedure. Endoscopic full-thickness resection appears to achieve a very high R0 resection rate. However, this technique absolutely requires a very skilled operator. Moreover, there is a risk of peritoneal seeding due to lar...Continue Reading

Citations

Apr 3, 2016·Gastrointestinal Endoscopy Clinics of North America·Hyung Hun Kim, Noriya Uedo
Jul 7, 2017·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Qiang ZhangSi-De Liu
Apr 17, 2018·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Nobutsugu AbeMasanori Sugiyama
Apr 26, 2017·World Journal of Clinical Oncology·Gandhi Lanke, Jeffrey H Lee
Apr 2, 2019·Cancer·Mark S Etherington, Ronald P DeMatteo
Jun 10, 2017·World Journal of Gastroenterology : WJG·Guan-Qun LiaoGuo-Xin Li
Nov 16, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Shanshan Wang, Lei Shen
Jun 25, 2016·World Journal of Gastroenterology : WJG·Hyuk Soon ChoiChang Duck Kim
Jun 26, 2020·Cancer Management and Research·Ruonan JiaoGuangming Huang
Dec 6, 2018·Gastroenterology Research and Practice·Cicilia MarcellaShakeel Sarwar
Sep 3, 2020·World Journal of Clinical Cases·Monjur Ahmed
Sep 22, 2017·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Cheal Wung Huh, Byung Wook Kim
Jan 13, 2017·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Nicola de'AngelisFrancesco Brunetti

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