PMID: 8944566Oct 1, 1996Paper

Endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localisation of insulinomas and gastrinomas

Gut
T ZimmerB Wiedenmann

Abstract

Endoscopic ultrasonography (EUS) and somatostatin receptor scintigraphy (SRS) can detect a high percentage of gastroenteropancreatic neuroendocrine tumours especially in the upper gastrointestinal tract. The ability of these procedures to localise primary tumour lesions and metastases of gastrinomas and insulinomas was evaluated in comparison with transabdominal ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI). In a prospective trial, patients with gastrinomas (n = 10) and insulinomas (n = 10) diagnosed by clinical signs and laboratory tests were assessed by EUS, SRS, US, CT and MRI. In 10 patients with gastrinoma and 10 patients with insulinoma, a total of 14 separate primary tumour lesions were histologically confirmed for each of the tumour entities. The mean diameter was 2.1 cm for gastrinomas and 1.5 cm for insulinomas. All insulinomas and nine gastrinoma lesions were located in the pancreas. Three gastrinomas were found in the duodenal wall, one in a periduodenal lymph node, and one in the liver, For gastrinomas, sensitivities were 79% with EUS, 86% with SRS and 29% with CT, US, and MRI. For insulinomas, sensitivities were 93% with EUS, 14% with SRS, 21% with CT and 7% with US and MRI. E...Continue Reading

References

Jul 5, 1992·The New England Journal of Medicine·T RöschV Schusdziarra
Jun 26, 1992·Deutsche medizinische Wochenschrift·K JosephR Arnold
Sep 1, 1992·Metabolism: Clinical and Experimental·E P KrenningS W Lamberts
Mar 15, 1990·The New England Journal of Medicine·M Pipeleers-MarichalP U Heitz
Nov 1, 1990·The New England Journal of Medicine·S W LambertsE P Krenning
Sep 1, 1986·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·T KazumiS Baba
Jan 1, 1981·Acta Radiologica: Diagnosis·A HemmingssonK Oberg
Feb 1, 1984·Radiology·D D StarkC W Deveney
Dec 1, 1993·Gastroenterology·H ScherüblB Wiedenmann
Mar 18, 1994·Deutsche medizinische Wochenschrift·E HöringH Bihl

❮ Previous
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Citations

Mar 6, 2012·European Journal of Nuclear Medicine and Molecular Imaging·Giovanna PepeArturo Chiti
Jul 23, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Håkan Geijer, Lars H Breimer
Apr 17, 2010·International Journal of Colorectal Disease·Sang Nam YoonJin Cheon Kim
Sep 12, 2000·Current Gastroenterology Reports·L Somogyi, G Mishra
Mar 12, 2003·Current Treatment Options in Gastroenterology·Patrick D. HungAnastasios A. Mihas
Aug 21, 2009·Pathology Oncology Research : POR·Hilda WongRichard J Epstein
Aug 28, 2004·Gastrointestinal Endoscopy·José Celso ArdenghAngelo Paulo Ferrari
Jul 19, 2001·The Surgical Clinics of North America·K Azimuddin, R S Chamberlain
Mar 29, 2001·European Journal of Radiology·J RickeB Wiedenmann
Dec 10, 1999·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·C De AngelisM Rizzetto
Oct 6, 1999·Journal of the American College of Surgeons·L A Hashimoto, R M Walsh
Aug 16, 2001·ANZ Journal of Surgery·M H MullanN W Thompson
Jan 22, 2003·Internal Medicine Journal·I D Norton, D B Jones
Dec 10, 1999·The New England Journal of Medicine·W R Brugge, J Van Dam
Nov 25, 2003·Cancer Biotherapy & Radiopharmaceuticals·Georg Riccabona, Clemens Decristoforo
Sep 25, 2001·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·K AmikuraS Matsuno
Jun 27, 2006·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Kristel de VogelaereGeorges Delvaux
Aug 8, 2006·Current Opinion in Gastroenterology·Andrew Y Wang, Nuzhat A Ahmad
Jan 21, 2012·Nuclear Medicine Communications·Yifan Zhang, Wengen Chen
Dec 25, 2007·Annals of Surgery·Mehrdad NikfarjamCarlos Fernández-del Castillo
May 13, 2005·Gut·J K RamageUNKNOWN UKNETwork for Neuroendocrine Tumours
Oct 4, 2006·Orphanet Journal of Rare Diseases·Francesca MariniMaria Luisa Brandi
Jul 12, 2013·European Journal of Medical Research·Thomas Günther LesserFrank Wolfram
Oct 26, 2011·Endocrine-related Cancer·Jaap J M TeunissenEric P Krenning
Jun 27, 2013·World Journal of Gastroenterology : WJG·Srinivas R PuliDavid Forcione
Jan 25, 2014·European Journal of Endocrinology·Pedro Iglesias, Juan J Díez
Sep 22, 2001·Clinical Imaging·A ChatziioannouL Vlachos
Apr 16, 1998·The British Journal of Radiology·A D KingC S Cockram
Nov 2, 2004·World Journal of Surgery·Charles A G Proye, Jonathan S Lokey
Aug 29, 2003·Mayo Clinic Women's Healthsource
Aug 31, 2000·Surgery·F J BerendsH J Bonjer
Apr 20, 2010·Expert Review of Endocrinology & Metabolism·Jean-Marc Guettier, Phillip Gorden
Mar 28, 2013·Expert Opinion on Medical Diagnostics·Craig A MunroeThomas J Savides
Jun 26, 2013·Annales d'endocrinologie·David TaiebUNKNOWN French Endocrine Society

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