Endoscopic ultrasonography in rectal linitis plastica

Gastrointestinal Endoscopy
I DumontierD Couturier

Abstract

Rectal linitis plastica (RLP) is a rare tumor with a poor prognosis. RLP can be a primary tumor, secondary to gastric linitis, or a metastatic form of breast or prostate carcinoma. Diagnosis is difficult because of nonspecific clinical and endoscopic findings and frequent negative biopsies (50%). The aim of this study was to evaluate the endosonographic appearance of RLP and to study the usefulness of endoscopic ultrasonography (EUS) in the follow-up of patients with RLP. Twenty-two video-recorded EUS examinations performed in 11 patients with histologically proven RLP were retrospectively studied. Response to conservative treatment was evaluated in three patients with secondary RLP. In every case of RLP, EUS showed a circumferential thickening of the rectal wall (mean 13 mm); the thickening was mainly seen in the submucosa and the muscularis propria. In nine cases EUS showed signs of locoregional involvement (perirectal fat infiltration [n = 6], ascites [n = 5], lymph nodes [n = 3]) which was not seen by CT. In follow-up evaluations, EUS showed a lack of response to treatment in two patients with RLP secondary to gastric linitis. In the remaining patient with RLP secondary to breast carcinoma, EUS at first showed no response. ...Continue Reading

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Citations

Sep 28, 2004·European Radiology·Borislav LaoutlievLene Simonsen
Aug 19, 2014·World Journal of Gastroenterology : WJG·Hong-Tan ChenYou-Ming Li
Jun 10, 2011·Gastroenterología y hepatología·Ana Zaida Gómez-MorenoJosé María Carrobles
Sep 12, 2009·Best Practice & Research. Clinical Gastroenterology·Alexis M P SchizasJohn Meenan
Mar 29, 2008·Gastroentérologie Clinique Et Biologique·Z Samlani-SebbaneK Krati
Mar 4, 2008·Gastroenterology Clinics of North America·Manoop S Bhutani
Jul 2, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Filippo VenturiniSalvatore Siena
Nov 5, 2003·Journal of Clinical Ultrasound : JCU·Yasutomo FujiiHideo Nagai
Aug 19, 2000·The American Journal of Gastroenterology·P NieboerH M van Dullemen
Jan 17, 2002·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ciaran F KeoghP Terry Phang

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