Endoscopic ultrasound-guided needle-based confocal laser endomicroscopy for diagnosis of solid pancreatic lesions (ENES): a pilot study

Endoscopy International Open
Pradermchai KongkamRungsun Rerknimitr

Abstract

Endoscopic ultrasound-guided needle-based confocal laser endomicroscopy (EUS-nCLE) has been shown to aid in the diagnosis of cystic pancreatic lesions. This is a pilot project to study its findings in patients with solid pancreatic lesions (SPLs) with a prospective single-blinded study design. Patients with SPLs undergoing trans-gastric EUS fine needle aspiration (EUS-FNA) from July 2013 to March 2014 were prospectively enrolled. The nCLE diagnoses were compared with the final diagnoses. Researchers learned about the EUS-nCLE findings from previously published studies and applied it to diagnose SPLs. In the meantime, the findings were recorded. In total, 22 patients were recruited (mean age 62.7 years, SD 13.8 years; 14 men and eight women). The mean maximal tumor diameter was 36.0 mm (SD 10.9 mm). EUS-nCLE yielded satisfactory images in all patients during the first EUS procedure and diagnosed benign and malignant SPLs in 3 and 19 patients, respectively. Final diagnoses of malignant SPLs were made in 19 patients. Benign SPLs were eventually diagnosed in three patients, with confirmed the cytology and disease stability during the 12-month follow-up period. At the end of the project, based on the results of this current study, E...Continue Reading

Citations

Feb 22, 2018·Cancers·Pujan Kandel, Michael B Wallace
Jan 21, 2017·World Journal of Gastroenterology : WJG·Andrada SeiceanRadu Seicean
Jul 25, 2019·Clinical Endoscopy·Yousuke NakaiKazuhiko Koike
Nov 8, 2016·World Journal of Gastroenterology : WJG·Andrew C Storm, Linda S Lee

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Software Mentioned

EUS
nCLE
SPSS

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