Endoscopic ultrasound staging of rectal cancer: diagnostic value before and following chemoradiation

Journal of Gastroenterology and Hepatology
Yaakov MaorBenjamin Avidan

Abstract

Endoscopic ultrasound (EUS) has been shown to be a reliable tool for staging rectal cancer. Nevertheless, the accuracy of EUS after chemoradiation remains unclear; therefore the purpose of the present paper was to compare the accuracy of EUS staging for rectal cancer before and following chemoradiation. Patients with rectal cancer undergoing EUS staging were stratified into two groups. Group I consisted of 66 patients who underwent surgery following EUS staging without preoperative chemoradiation. Group II consisted of 25 patients who had EUS evaluation following chemoradiation. The EUS staging was compared to surgical/pathological staging. The accuracy of the T staging for group I was 86% (57/66). Inaccurate staging was mainly associated with overstaging EUS T2 tumors. The accuracy of the N staging for group I was 71% (47/66). The accuracy of EUS for a composite T and N staging relevant to treatment decisions in group I was 91%. In group II, the accuracy of T and N staging was 72% (18/25) and 80% (20/25), respectively. Overstaging EUS T3 tumors accounted for most inaccurate staging. The EUS staging predicted post-chemoradiation T0N0 stage correctly in only 50% of cases. Preoperative staging of rectal cancer by EUS is a useful ...Continue Reading

References

Jul 1, 1991·The British Journal of Surgery·B NapoleonJ C Souquet
Dec 1, 1993·American Journal of Surgery·S M SentovichM A Christensen
Jul 1, 1993·Gastrointestinal Endoscopy·E ChoK Kawai
Feb 1, 1993·Diseases of the Colon and Rectum·U HerzogJ P Schuppisser
Jan 1, 1996·Diseases of the Colon and Rectum·P R WilliamsonA Ferrara
Apr 3, 1997·The New England Journal of Medicine·UNKNOWN Swedish Rectal Cancer TrialN Wilking
Jan 1, 1997·International Journal of Colorectal Disease·M SailerA Thiede
Oct 23, 1997·Diseases of the Colon and Rectum·M SailerA Thiede
Sep 28, 1998·Diseases of the Colon and Rectum·A Habr-GamaJ Gama-Rodrigues
Jul 27, 1999·The British Journal of Surgery·S A Norton, M G Thomas
Mar 14, 2000·Annals of Surgery·J Garcia-AguilarD A Rothenberger
Jun 30, 2000·Journal of Clinical Gastroenterology·P MaroneA Tempesta
Oct 5, 2001·Diseases of the Colon and Rectum·J C KimM G Lee
Jan 12, 2002·Diseases of the Colon and Rectum·Julio Garcia-AguilarRobert D Madoff
Feb 21, 2003·The British Journal of Surgery·S G MackayM J Solomon
Dec 23, 2003·The American Journal of Gastroenterology·Arvydas VanagunasSteven J Stryker

❮ Previous
Next ❯

Citations

May 24, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Daniel C DaminGilberto Schwartsmann
Nov 29, 2007·Nature Clinical Practice. Gastroenterology & Hepatology·Julia K LeBlanc
Nov 30, 2006·Current Opinion in Gastroenterology·Manoop S Bhutani
Oct 27, 2009·Future Oncology·Justin Mc YeungAlexander G Heriot
Nov 26, 2009·World Journal of Gastroenterology : WJG·Gianni MezziPier Alberto Testoni
Feb 6, 2010·World Journal of Gastroenterology : WJG·Taylan Kav, Yusuf Bayraktar
Mar 18, 2011·World Journal of Gastroenterology : WJG·Abdus Samee, Chelliah Ramachandran Selvasekar
Oct 10, 2013·World Journal of Gastroenterology : WJG·Paola De Nardi, Michele Carvello
Mar 6, 2012·Seminars in Radiation Oncology·Eliane C M ZeestratenCorrie A M Marijnen
Jul 26, 2011·Clinics and Research in Hepatology and Gastroenterology·Pietro MaroneGiovanni Battista Rossi
May 10, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Davide RavizzaCristiano Crosta
Aug 12, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J E RyanA G Heriot
Feb 10, 2016·Gastroenterology Research and Practice·Anna FábiánZoltán Szepes
Sep 12, 2009·Best Practice & Research. Clinical Gastroenterology·Alexis M P SchizasJohn Meenan
Aug 23, 2008·Gastrointestinal Endoscopy·Ferga C GleesonMichael J Levy
Jul 1, 2008·Journal of the American College of Surgeons·Jung Wook HuhSeung-Kook Sohn
Sep 18, 2007·Clinical Oncology : a Journal of the Royal College of Radiologists·B J Cummings
Nov 2, 2007·Advances in Surgery·Julia K LeBlancStuart Sherman
Apr 22, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S MemonA G Heriot
Aug 21, 2013·Orvosi hetilap·Renáta BorZoltán Szepes
Aug 16, 2011·Gastrointestinal Endoscopy·Ferga C GleesonMichael J Levy
Mar 14, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nancy N Baxter, Julio Garcia-Aguilar
Jul 12, 2011·Techniques in Coloproctology·O J MorrisS Smith
Aug 30, 2014·World Journal of Gastroenterology : WJG·Andrea Vignali, Paola De Nardi
Jul 21, 2009·Diseases of the Colon and Rectum·Marc Beer-GabelBinjamin Avidan
Apr 17, 2017·Oncotarget·Sheng WangShupeng Wang
Jul 29, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Shiyong LinGuoliang Xu
Aug 10, 2011·Diseases of the Colon and Rectum·Carlos PastorJose Luis Hernandez-Lizoain
Nov 17, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·V Raman Muthusamy, Kenneth J Chang

❮ Previous
Next ❯

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