Endoscopic versus surgical treatment for pancreatic pseudocysts: Systematic review and meta-analysis

Medicine
Galileu Ferreira FariasEduardo Guimarães Hourneaux de Moura

Abstract

This systematic review and meta-analysis aims to compare surgical and endoscopic treatment for pancreatic pseudocyst (PP). The researchers did a search in Medline, EMBASE, Scielo/Lilacs, and Cochrane electronic databases for studies comparing surgical and endoscopic drainage of PP s in adult patients. Then, the extracted data were used to perform a meta-analysis. The outcomes were therapeutic success, drainage-related adverse events, general adverse events, recurrence rate, cost, and time of hospitalization. There was no significant difference between treatment success rate (risk difference [RD] -0.09; 95% confidence interval [CI] [0.20,0.01]; P = .07), drainage-related adverse events (RD -0.02; 95% CI [-0.04,0.08]; P = .48), general adverse events (RD -0.05; 95% CI [-0.12, 0.02]; P = .13) and recurrence (RD: 0.02; 95% CI [-0.04,0.07]; P = .58) between surgical and endoscopic treatment.Regarding time of hospitalization, the endoscopic group had better results (RD: -4.23; 95% CI [-5.18, -3.29]; P < .00001). When it comes to treatment cost, the endoscopic arm also had better outcomes (RD: -4.68; 95% CI [-5.43,-3.94]; P < .00001). There is no significant difference between surgical and endoscopic treatment success rates, adverse e...Continue Reading

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Citations

Nov 17, 2019·Digestive Diseases and Sciences·M MinghettiV Tonini
Mar 21, 2020·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·M UddA Kokkola
Feb 23, 2020·Journal of Pediatric Gastroenterology and Nutrition·Quin Y LiuVeronique D Morinville
Jun 18, 2019·World Journal of Gastrointestinal Endoscopy·Diogo Turiani Hourneaux de MouraChristopher C Thompson
Mar 5, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·J C ChenMary E Dillhoff
Jun 6, 2020·Current Gastroenterology Reports·Raj DalsaniaSaurabh Chawla
Dec 29, 2020·World Journal of Gastroenterology : WJG·Igor Mendonça ProençaEduardo Guimarães Hourneaux de Moura
Nov 28, 2020·World Journal of Gastroenterology : WJG·Fang LiuWen Li
Jun 1, 2021·Annals of the Royal College of Surgeons of England·S S YathamM H Sodergren
Jul 2, 2021·World Journal of Gastrointestinal Surgery·Cosmas Rinaldi Adithya LesmanaRino Alvani Gani
Aug 7, 2021·World Journal of Gastrointestinal Surgery·Nian-Jun XiaoWen Li

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Methods Mentioned

BETA
pancreatectomy

Software Mentioned

RevMan

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