Endoscopist administered propofol for upper-GI EUS is safe and effective: a prospective study in 500 patients

Gastrointestinal Endoscopy
Ian F YusoffAnand V Sahai

Abstract

The administration of propofol for endoscopic sedation by a qualified person, other than the endoscopist, is safe and effective. The aim of this study was to determine if propofol can be administered safely and effectively by the endoscopist performing the procedure. All patients referred for upper-GI EUS were eligible for inclusion in the study. Exclusion criteria included the following: age less than 18 years, American Society of Anesthesiology physical status class greater than 2, a potential for difficulty in airway maintenance, and allergy to propofol constituents. The endoscopist administered propofol as an intravenous bolus followed by a constant infusion. Adverse events, drug dosage, complications, and patient/endoscopist satisfaction were recorded. A total of 500 patients (285 women, 215 men; mean age 53.4 [14.8 years]) were enrolled. Mean propofol dose was 301 mg (range 100-1000 mg). Mean procedure time was 19 minutes (range 3-70 minutes). The required examination was completed in all cases. There was no major adverse event. Oxygen desaturation (oxygen saturation < 95%) occurred in 16 (3%) patients. There were 4 (1%) cases of mild hypoxemia (saturation < 90%) but no case of severe hypoxemia (saturation <85%). The endo...Continue Reading

Associated Clinical Trials

References

Oct 1, 1978·Anesthesiology·W D OwensE L Spitznagel
May 26, 2001·Gastrointestinal Endoscopy·D B NelsonUNKNOWN American Society for Gastrointestinal Endoscopy. Technology Committee
Feb 28, 2002·The American Journal of Gastroenterology·Gabu BhardwajJuan Baralt
Apr 20, 2002·Anesthesiology·UNKNOWN American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists
May 17, 2002·The American Journal of Gastroenterology·Douglas K RexDebra Helper
Jul 27, 2002·Journal of Pediatric Gastroenterology and Nutrition·Jose L MartinezCarol Marquez
Oct 25, 2002·Gastrointestinal Endoscopy·Douglas O FaigelUNKNOWN Standards Practice Committe, American Society for Gastrointestinal Endoscopy
Nov 5, 2003·Gastrointestinal Endoscopy·Lawrence B CohenKenneth M Miller

❮ Previous
Next ❯

Citations

Jun 7, 2012·Journal of Clinical Monitoring and Computing·Suzanne B KaranDenham S Ward
Dec 19, 2008·Nature Clinical Practice. Gastroenterology & Hepatology·Lawrence B Cohen
Apr 15, 2010·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Marsha L Cirgin Ellett
May 27, 2010·World Journal of Gastroenterology : WJG·Lorella Fanti, Pier-Alberto Testoni
May 17, 2014·World Journal of Gastroenterology : WJG·Danny G Cheriyan, Michael F Byrne
Jan 25, 2012·Digestive Diseases and Sciences·Abdul Hamid El ChaficDouglas K Rex
May 23, 2012·Digestive Diseases and Sciences·Chang Hwan Choi
Jun 28, 2011·Gastrointestinal Endoscopy·Massimo AgostoniPier Alberto Testoni
Jun 7, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Lorella FantiUNKNOWN Italian Society of Digestive Endoscopy Sedation Commission
Dec 21, 2010·Gastrointestinal Endoscopy·Chang Kyun LeeSun-Joo Kim
Dec 8, 2009·Gastrointestinal Endoscopy·John J VargoPaul Y Kwo
Dec 8, 2009·Gastroenterology·John J VargoUNKNOWN American Society for Gastrointestinal Endoscopy
Jul 18, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Gregory A CotéSreenivasa S Jonnalagadda
Jun 25, 2009·Gastroenterology·Douglas K RexNizam Meah
Oct 17, 2008·Gastrointestinal Endoscopy Clinics of North America·Douglas K RexEmely Eid
Oct 5, 2007·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·M AgostoniP A Testoni
Aug 30, 2007·Gastrointestinal Endoscopy·Daniel KüllingWerner Inauen
Apr 3, 2007·Gastrointestinal Endoscopy Clinics of North America·John J Vargo
Nov 14, 2006·Gastrointestinal Endoscopy Clinics of North America·James Aisenberg, Lawrence B Cohen
Oct 20, 2006·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·L FantiP A Testoni
Nov 26, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·John J VargoPaul Y Kwo
Mar 4, 2014·Mayo Clinic Proceedings·Emmanuel C Gorospe, Amy S Oxentenko
Dec 6, 2005·Journal of Cardiothoracic and Vascular Anesthesia·John E Ellis, Sheela S Pai
Mar 3, 2011·Orvosi hetilap·Katalin Müllner, Zsolt Tulassay
Jul 13, 2016·The American Journal of Gastroenterology·James BuxbaumJohn Vargo
Apr 26, 2014·Clinical Endoscopy·Eun Hye Kim, Sang Kil Lee
Apr 26, 2014·Clinical Endoscopy·Tae Hoon Lee, Chang Kyun Lee
Mar 24, 2012·World Journal of Gastrointestinal Endoscopy·Yosuke MurakiMasao Ichinose
Jul 29, 2018·Digestive Diseases and Sciences·Su Jung HanSun-Joo Kim
Jun 19, 2008·The American Journal of Gastroenterology·Hala FatimaThomas F Imperiale
Dec 4, 2009·The American Journal of Gastroenterology·John J VargoPaul Y Kwo
May 23, 2012·The American Journal of Gastroenterology·John J VargoLawrence R Schiller
Mar 15, 2006·Current Opinion in Anaesthesiology·Kate Leslie, Christopher A Stonell
Aug 4, 2010·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Marsha L Ellett
Feb 15, 2012·European Journal of Gastroenterology & Hepatology·Eduardo Redondo-CerezoJavier de Teresa
Oct 13, 2005·Current Opinion in Gastroenterology·Wahid Wassef, Ramon Rullan
Mar 20, 2019·The Kaohsiung Journal of Medical Sciences·Joo Hyung KimJin Hong Kim
May 29, 2015·World Journal of Gastroenterology : WJG·Seungho LeeSeon Mee Park
Oct 31, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Takuji GotodaHaruhiro Inoue

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva
S Sáenz-LópezJ A Solís Herruzo
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Brian J UlmerDouglas K Rex
© 2021 Meta ULC. All rights reserved