Endosteal Biologic Augmentation for Surgical Fixation of Displaced Femoral Neck Fractures

Journal of Orthopaedic Trauma
Lionel E LazaroDean G Lorich

Abstract

To report outcomes of a cohort with displaced femoral neck fractures (FNFs) treated with a length/angle-stable construct augmented with an endosteal fibular allograft serving as a biologic dowel. Prospective. Level I Trauma Center. The study group consists of 27 patients with isolated FNF surgically treated by a single surgeon. Open reduction of the femoral neck, fixed with a length- and angle-stable construct of 2 fully threaded cannulated screws augmented with an endosteal fibular allograft serving as a biologic dowel. Clinical and radiographic outcomes of the fixation construct and the viability of both the femoral head and the fibular allograft, host response to the allograft and osseous union were evaluated using a specialized sequence of contrast-enhanced magnetic resonance imaging (MRI) obtained at 3 and 12 months postoperatively. This construct resulted in high union rates (89%; 24 of 27). Two patients suffered early catastrophic failure and 1 patient developed fracture nonunion, all of wish underwent uneventful conversion to total hip arthroplasty. Three additional patients (11%) had removal of symptomatic implants. The clinical and radiographic outcomes were excellent. Twelve-month MRIs revealed either partial or comp...Continue Reading

References

May 1, 1986·The Journal of Bone and Joint Surgery. British Volume·O N NagiS K Marya
Jan 1, 1994·The Journal of Bone and Joint Surgery. American Volume·G L Lu-YaoJ E Wennberg
Oct 13, 1998·The Journal of Bone and Joint Surgery. British Volume·O N NagiV G Goni
Apr 17, 1999·Journal of Orthopaedic Trauma·J I KauffmanK J Koval
Jun 16, 2001·The Journal of Bone and Joint Surgery. American Volume·B GurneyD Rivero
Sep 5, 2003·The Journal of Bone and Joint Surgery. American Volume·Mohit BhandariGordon H Guyatt
Sep 6, 2005·The Journal of Arthroplasty·Piergiorgio MarchettiLuciano Silvello
May 6, 2006·The Journal of the American Academy of Orthopaedic Surgeons·William MacaulayKhaled J Saleh
Jan 2, 2007·Archives of Orthopaedic and Trauma Surgery·Michael J GardnerDean G Lorich
Oct 4, 2008·The Journal of the American Academy of Orthopaedic Surgeons·Ryan G MiyamotoJoseph D Zuckerman
Oct 1, 2010·Journal of Magnetic Resonance Imaging : JMRI·K M KochK F King
Oct 29, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K M KochK F King
Aug 25, 2011·AJR. American Journal of Roentgenology·Catherine L HayterHollis G Potter
Sep 3, 2011·Journal of Orthopaedic Trauma·Hassan R MirGeorge Haidukewych
Jan 16, 2014·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Matthew C WendtRobert R Trousdale

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Citations

Feb 11, 2018·Archives of Orthopaedic and Trauma Surgery·Yoram A WeilAmal Khoury
Dec 13, 2018·Journal of Orthopaedic Trauma·Ashley E LevackDavid L Helfet
Jul 30, 2019·Orthopedics·Naomi E GadinskyLionel E Lazaro
Jun 3, 2019·The Journal of the American Academy of Orthopaedic Surgeons·Thomas M LargeMichael J Gardner
Jun 18, 2019·The Journal of the American Academy of Orthopaedic Surgeons·Geoffrey Marecek, Hugo Centomo
Jan 27, 2018·Journal of Orthopaedic Trauma·Clay A SpitlerMatthew L Graves
Aug 30, 2017·Archives of Orthopaedic and Trauma Surgery·Lionel E LazaroDean G Lorich
Jul 22, 2017·Archives of Orthopaedic and Trauma Surgery·Adham ElgeidiNabil El Moghazy
Aug 23, 2019·Techniques in Hand & Upper Extremity Surgery·Joseph E ManziDavid M Dines
Mar 30, 2021·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Humaid Al FariiJennifer Mutch

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