Endosymbiont genomes yield clues of tubeworm success

The ISME Journal
Yuanning LiKenneth M Halanych

Abstract

Forty years after discovery of chemosynthetic symbiosis in the tubeworm Riftia pachyptila, how organisms maintain their unique host-symbiont associations at the cellular level is still largely unknown. Previous studies primarily focus on symbionts associated with host lineages living in hydrothermal vents. To understand physiological adaptations and evolution in these holobiont systems in markedly different habitats, we characterized four novel siboglinid-symbiont genomes spanning deep-sea seep and sedimented environments. Our comparative analyses suggest that all sampled siboglinid chemoautotrophic symbionts, except for frenulate symbionts, can use both rTCA and Calvin cycle for carbon fixation. We hypothesize that over evolutionary time siboglinids have been able to utilize different bacterial lineages allowing greater metabolic flexibility of carbon fixation (e.g., rTCA) enabling tubeworms to thrive in more reducing habitats, such as vents and seeps. Moreover, we show that sulfur metabolism and molecular mechanisms related to initial infection are remarkably conserved across chemoautotrophic symbionts in different habitats. Unexpectedly, we find that the ability to use hydrogen, as an additional energy source, is potentially...Continue Reading

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Citations

Oct 20, 2019·Applied and Environmental Microbiology·Jessica H MitchellKathleen M Scott
Mar 15, 2019·Nature Reviews. Microbiology·Gregory J Dick
Nov 17, 2020·Environmental Microbiology Reports·Camille Brzechffa, Shana K Goffredi
Sep 22, 2020·Molecular Biology and Evolution·Jack Chi-Ho IpJian-Wen Qiu
Aug 11, 2021·Environmental Microbiology Reports·Tal Zvi-KedemMaxim Rubin-Blum
Oct 23, 2020·The Journal of Organic Chemistry·Kevin CalabroOlivier P Thomas
Aug 6, 2021·Annual Review of Microbiology·E Maggie SoginNicole Dubilier

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Datasets Mentioned

BETA
AFOC00000000
LMX100000000

Software Mentioned

RAxML
ProtTest
TREEBASE
MAFFT
sh
AlignmentCompare
CheckM
MetaPlatanus
Gblocks
BLAST

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