Endothelial cell loss and complication rates with combined Descemets stripping endothelial keratoplasty and cataract surgery in a UK centre

Eye
S M JonesE J Hollick

Abstract

To report 6-month, 1- and 2-year endothelial cell loss (ECL), intra- and postoperative complications in a large series of patients undergoing either Descemets stripping endothelial keratoplasty (DSEK) or a combined phacoemulsification and DSEK in a UK centre. Patients undergoing DSEK with or without concurrent cataract surgery were included in this retrospective study. Surgeries were performed between January 2006 and May 2013. Main outcomes included intra- and postoperative complications and percentage ECL. DSEK was performed in 226 eyes (210 patients). Of these, 141 eyes (126 patients) underwent DSEK alone and 85 eyes (84 patients) underwent DSEK combined with cataract surgery. Excluding complex anterior segment pathology the mean percentage ECL at 6, 12 and 24 months was 40.5±13.4, 45.1±14.6 and 53.1±13.0 in the DSEK group and 40.7±15.4, 42.6±15.3 and 49.6±16.5 in patients undergoing the combined procedure, respectively. There was no significant difference in percentage ECL at 6 or 24 months between the two groups both in complex and routine cases. Intraoperative complications occurred in four patients undergoing DSEK and three undergoing combined procedure. Postoperative complication rates did not reach statistical signific...Continue Reading

References

May 29, 2010·The British Journal of Ophthalmology·Marianne O PriceFrancis W Price
Apr 21, 2012·Survey of Ophthalmology·Arundhati AnshuFrancis W Price

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Citations

Nov 27, 2019·Current Opinion in Ophthalmology·Caterina SarnicolaVincenzo Sarnicola
Aug 8, 2021·Journal of Clinical Medicine·Orlaith McGrathJane Ashworth

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