Endotherapy is effective for pancreatic ductal disruption: A dual center experience

Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Rohit DasAli A Siddiqui

Abstract

Pancreatic duct (PD) disruptions occur as a result of different etiologies and can be managed medically, endoscopically, or surgically. The aim of this study was to provide an evaluation on the efficacy of endotherapy for treatment of PD disruption in a large cohort of patients and identify factors that predict successful treatment outcome. We retrospectively evaluated consecutive patients who underwent endoscopic retrograde pancreatography (ERP) for transpapillary pancreatic stent placement for PD disruption from 2008 to 2013 at two tertiary referral institutions. PD disruption was defined as extravasation of contrast from the pancreatic duct as seen on ERP. Therapeutic success was defined by resolution of PD leak on ERP, clinical, and/or imaging evaluation. We evaluated 107 patients (58% male, mean age 53 years) with PD disruption. Etiologies of PD disruption were acute pancreatitis (36%), post-operative (31%), chronic pancreatitis (29%), and trauma (4%). PD disruption was successfully bridged by a stent in 45 (44%) patients. Two patients developed post-sphincterotomy bleeding, two had stent migration, and two patients died as a result of post-ERP related complications. Placement of a PD stent was successful in 103/107 (96%) ...Continue Reading

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Citations

Apr 20, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Ichiro Yasuda, Kosuke Takahashi
Jul 1, 2020·Digestive Diseases and Sciences·Hester C TimmerhuisUNKNOWN Dutch Pancreatitis Study Group
Sep 2, 2019·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Sven M van DijkUNKNOWN Dutch Pancreatitis Study Group

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