Endotherapy of early onset idiopathic chronic pancreatitis: results with long-term follow-up

Gastrointestinal Endoscopy
Armando GabbrielliG Costamagna

Abstract

Idiopathic chronic pancreatitis that presents at age 35 years or younger has been classified as early onset type and is often characterized by chronic severe pain. Endotherapy, with drainage of the main pancreatic duct, can lead to control of pain if ductal hypertension is an important cause. Long-term results of endotherapy in patients with early onset idiopathic chronic pancreatitis are reported herein. This retrospective study consists of 11 patients (6 men, 5 women; mean age 24.2 years, range 16-34 years) treated endoscopically in a 6.5-year period. The indication for treatment was pain in all patients and all had a dilated main pancreatic duct on pancreatography. The objectives of endoscopic treatment were to obtain good drainage of the pancreatic duct and complete clearance of ductal stones. Treatment was successful in all patients with no procedure-related mortality and with mild complications. Seven patients remained free of pain relapses after a mean follow-up of 78.3 months (37-116 months). Seven relapses of pain were recorded in the remaining 4 patients. Endoscopic retreatment was successful in all cases. The difference between the number of hospitalizations during the year before treatment (mean 2.2, range 1-9) and ...Continue Reading

Citations

Mar 26, 2005·Surgical Endoscopy·G C VitaleB Hammond
Dec 25, 2010·Therapeutic Advances in Gastroenterology·Haritha Avula, Stuart Sherman
Feb 16, 2007·The New England Journal of Medicine·Djuna L CahenMarco J Bruno
Dec 30, 2011·The Korean Journal of Internal Medicine·Damien Meng Yew Tan, Stuart Sherman
Mar 16, 2013·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Takao ItoiFuminori Moriyasu
Aug 9, 2007·Journal of Gastroenterology and Hepatology·Sanjay K BhadadaDeepak K Bhasin
Jan 25, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michol A CooperDana K Andersen
Apr 14, 2020·European Journal of Gastroenterology & Hepatology·Rajesh SanjeeviSudipta Dhar Chowdhury
Oct 31, 2006·World Journal of Gastroenterology : WJG·Raffaele PezzilliRoberto Corinaldesi
Oct 15, 2013·Journal of Hepato-biliary-pancreatic Sciences·Takao ItoiKazuhiko Kasuya
May 7, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Deepak K BhasinBirinder Nagi

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