PMID: 784892Sep 1, 1976

Endotoxin protein: a B-cell mitogen and polyclonal activator of C3H/HeJ lymphocytes

The Journal of Experimental Medicine
B M Sultzer, G W Goodman


A cell wall protein that is ordinarily complexed to the lipopolysaccharide endotoxin in gram-negative bacteria has been separated by the use of aqueous phenol. The protein is active as a B-cell mitogen and polyclonal activator of murine lymphocytes including the C3H/HeJ strain which is a nonresponder to lipoplysaccharide or lipid A.


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