PMID: 8594954Dec 1, 1995Paper

Endotracheal intubation with propofol and fentanyl

Der Anaesthesist
H W StriebelG Brummer

Abstract

The routine use of succinylcholine for endotracheal intubation is being increasingly questioned. Initial studies have suggested that a combination of propofol and alfentanil without a muscle relaxant can provide good intubating conditions. However, most of these initial studies either did not have a double-blind design or did not include a control group with muscle relaxants. In this study, intubation conditions using fentanyl/propofol without a muscle relaxant were compared with the combinations of fentanyl/propofol/succinylcholine and sodium thiopental/succinylcholine. MATERIAL AND METHODS. Following approval from the local ethics committee and written consent, 100 gynaecological patients (ASA I, II) were included in this study. The study was carried out in a double blind, randomized and prospective manner. Black perfusor syringes and extension sets were used, and the drugs administered were diluted to equal volumes. For induction, group 1 (n = 25) received 0.1 mg fentanyl, 1 mg vecuronium, sodium thiopental (demand-adapted) and succinylcholine 1 mg/kg; group 2 (n = 25) received 0.1 mg fentanyl and propofol (demand-adapted); group 3 (n = 25) received 0.2 mg fentanyl and propofol (demand-adapted); group 4 (n = 25) received 0.1...Continue Reading

Citations

Jun 10, 2010·Indian Journal of Anaesthesia·Safiya I Shaikh, Vijayalaxmi P Bellagali
Jan 12, 2020·Anaesthesia Critical Care & Pain Medicine·Benoît PlaudBertrand Debaene

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