Endovascular Repair and Adjunctive Immunosuppressive Therapy of Aortic Involvement in Behçet's Disease

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
O BalciogluH Posacioglu

Abstract

Aortic aneurysm is a serious problem in Behçet's disease, but open surgical therapy carries the risk of recurrent pseudoaneurysm. Here the outcomes of endovascular repair and adjunctive immunosuppressive therapy for aortic disease in Behçet's disease are presented. This was a retrospective study. Between 2002 and 2012, nine patients with Behçet's disease (8 male, median age 41 years, range 33-60 years) were treated by endovascular stent grafting for abdominal or thoraco-abdominal aortic pseudoaneurysm. Computed tomography angiography revealed infrarenal pseudoaneurysm in six (66.6%) patients and suprarenal pseudoaneurysm in three (33.3%). Patients received immunosuppressive therapy with oral prednisolone (60 mg/day) and cyclophosphamide (200 mg/day) for 2 weeks or more before the procedure, and intravenous hydrocortisone (200 mg/day) combined with cyclophosphamide (200 mg/day) for 3 days after the procedure. Thereafter, oral immunosuppressive therapy was continued for 2 years. A straight tube graft was implanted in seven patients and a bifurcated graft in two patients. Two stage procedures (debranching before endovascular therapy) were performed in three patients for thoraco-abdominal aortic pseudoaneurysms. Stent grafting was ...Continue Reading

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Citations

Jan 16, 2018·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Yohei YamamotoToshifumi Kudo
Jan 31, 2020·Journal of Cardiothoracic Surgery·Zeyi ChengYingqiang Guo
Oct 4, 2019·International Angiology : a Journal of the International Union of Angiology·Ahmed MousaAhmed M Odeh
Dec 1, 2018·Internal and Emergency Medicine·Giacomo EmmiDomenico Prisco
Apr 2, 2020·VASA. Zeitschrift für Gefässkrankheiten·Chen-Hong LinJian-Long Guan
Jan 11, 2020·Frontiers in Immunology·Alessandra BettiolGiacomo Emmi
Apr 24, 2018·Annals of Vascular Diseases·Hiroyuki Ishibashi
Apr 1, 2017·Jornal Vascular Brasileiro·Nathalia Leslie Albanez Rodrigues de SouzaAna Terezinha Guillaumon
May 5, 2018·Journal of Vascular Surgery Cases and Innovative Techniques·Mohammed HamoudaMahmoud B Malas
Jun 3, 2020·Journal of Vascular Surgery·Julien GaudricFabien Koskas

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