Endovascular Thrombectomy >24-hr From Stroke Symptom Onset

Frontiers in Neurology
Nathan W ManningAndrew Cheung

Abstract

Background: Trials have demonstrated efficacy for endovascular thrombectomy (EVT) for anterior circulation acute ischaemic stroke (AIS) up to 24-h from symptom onset. The magnitude of effect suggests benefit may exist beyond 24-h. Objectives: To perform a retrospective review of all patients undergoing EVT for anterior circulation LVO stroke beyond 24-h from symptom onset and assess safety and efficacy. Methods:A prospectively maintained database of EVT patients treated at two comprehensive stroke centers between January 2016 and December 2017 was retrospectively screened. Patients undergoing EVT for anterior circulation AIS >24-h from symptom onset were selected. Results: A total of 429 AIS patient underwent EVT in the study period. Five patients treated >24-h from symptom onset were identified. The median age was 72 (range 42-84); median ASPECTS 8 (range 6-8); median baseline-NIHSS 9 (range 4-17); and median time from symptom onset to groin puncture 44 h and 55 min (range 25:07-90:10). One patient underwent CT perfusion imaging. The remaining four patients were selected based on non-contrast CT brain and CT-angiography. Two patients had tandem cervical carotid lesions and underwent acute stenting. Modified thrombolysis in cer...Continue Reading

References

Apr 14, 2007·Annals of Neurology·Jessica C TanMax Wintermark
May 10, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L DoradoA Dávalos
Jan 13, 2015·International Journal of Stroke : Official Journal of the International Stroke Society·Hayley M WheelerUNKNOWN DEFUSE 2 Investigators
Sep 28, 2016·JAMA : the Journal of the American Medical Association·Jeffrey L SaverUNKNOWN HERMES Collaborators
Aug 11, 2017·Stroke; a Journal of Cerebral Circulation·Marcelo Rocha, Tudor G Jovin
Nov 14, 2017·The New England Journal of Medicine·Raul G NogueiraUNKNOWN DAWN Trial Investigators
Jan 25, 2018·The New England Journal of Medicine·Gregory W AlbersUNKNOWN DEFUSE 3 Investigators

❮ Previous
Next ❯

Citations

Apr 3, 2021·Therapeutic Advances in Neurological Disorders·Peter B SpornsMarios Psychogios
Nov 5, 2021·Journal of Neurointerventional Surgery·Ilaria CasettaUNKNOWN Italian Registry of Endovascular Thrombectomy in Acute Stroke (IRETAS)

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.