Endovascular Thrombectomy in the Elderly: Do Radiological and Clinical Outcomes Differ from Those in Younger Patients? A Prospective Single-Center Experience

Cerebrovascular Diseases
Mehdi K RezaiMartin W Kurz

Abstract

Endovascular treatment (EVT) has emerged as the gold standard therapy for stroke due to large vessel occlusion (LVO). There is however limited evidence to suggest that similar efficacy can be expected in elderly patients. We aimed to assess the efficacy and safety of EVT in elderly patients (aged > 80), comparing outcomes to younger patients (aged < 80). A total of 195 patients with LVO stroke treated with EVT were included and dichotomized by age. We compared neurological improvement, clinical 90 day outcome, technical recanalization rates, procedure-related complications, and mortality in between the groups. Both groups showed equally marked neurological improvement. A favorable outcome modified Rankin Scale (mRS < 2) was seen in 28% of the elderly patients compared to 46% of the younger patients (p = 0.01). mRS 0-3 was seen in 46% of the elderly patients and 58% of the younger patients (p = 0.09). The rates of successful technical recanalization did not differ between the groups and there were no differences in procedural complication rates or incidence of symptomatic intracranial bleeding. Three-month mortality rates were however higher in the elderly group. EVT in the elderly resulted in equally notable neurological improv...Continue Reading

Citations

Mar 20, 2020·Stroke; a Journal of Cerebral Circulation·María I PedrazaJuan F Arenillas
Jun 24, 2020·Frontiers in Neurology·Hisham SalahuddinMouhammad A Jumaa
Apr 14, 2020·Acta Neurologica Scandinavica·Mehdi K RezaiMartin W Kurz
Mar 31, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Lorenzo RicciSabrina Anticoli
Dec 31, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Yen-Jun LaiChih-Wei Tang

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