Endovascular treatment of renal artery stenosis improves contralateral renal hypertrophy with nephrotic syndrome

CEN Case Reports
Hiromichi WakuiSatoshi Umemura

Abstract

Nephrotic syndrome due to renovascular hypertension is uncommon. We herein report a case of nephrotic syndrome associated with unilateral atherosclerotic renal artery stenosis. A 76-year-old woman who had been taking antihypertensive medication for more than 15 years was referred to our hospital for treatment of uncontrolled hypertension and massive proteinuria in the nephrotic range. An abdominal bruit was heard, and laboratory findings showed high plasma renin activity and hypokalemia. Renal computed tomography angiography showed severe stenosis of the ostium of the right renal artery and an atrophic right kidney. The left renal artery was normal and the left kidney was compensatorily enlarged. After admission, we started treatment with an angiotensin II receptor blocker and subsequently performed percutaneous transluminal renal angioplasty with renal artery stent placement. As a result, her blood pressure became well controlled and the massive proteinuria disappeared. In addition, her stenotic-side renal atrophy was resolved, concomitant with an improvement in her renal function. The contralateral renal hypertrophy was also resolved.

References

Jun 1, 1994·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M SekkarieP Peterson
Jul 1, 1996·Internal Medicine·H OgataK Shimamoto
Jun 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A M Alkhunaizi, A Chapman
Mar 29, 2003·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Fumihiko TakahashiKenjiro Kikuchi
Jun 7, 2006·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Bassam AlchiFumitake Gejyo
Aug 18, 2006·Current Opinion in Nephrology and Hypertension·Manuel Praga, Enrique Morales
Nov 13, 2009·The New England Journal of Medicine·UNKNOWN ASTRAL InvestigatorsJohn Scoble
Jul 30, 2011·Current Opinion in Cardiology·Pascal Meier

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

© 2022 Meta ULC. All rights reserved