Endurance training-induced increase in circulating irisin levels is associated with reduction of abdominal visceral fat in middle-aged and older adults

PloS One
Eri Miyamoto-MikamiMotoyuki Iemitsu

Abstract

To elucidate the effects of endurance training on circulating irisin levels in young and middle-aged/older adults, and to determine the association between endurance training-induced alteration of irisin and reduction in body fat. Twenty-five healthy young (age 21 ± 1 years; 16 men, 9 women) and 28 healthy middle-aged/older adults (age 67 ± 8 years; 12 men, 16 women) participated in the study. Each age cohort was divided into two groups: the endurance-training group (14 young, 14 middle-aged/older) and the control group. Subjects in the training groups completed an 8-week endurance-training program (cycling at 60-70% peak oxygen uptake [V̇O2peak] for 45 min, 3 days/week). Before and after the intervention, we evaluated serum irisin level, V̇O2peak, and body composition. The increase in V̇O2peak in the young and middle-aged/older training groups after the intervention period was significantly greater than those in the young and middle-aged/older control groups (P < 0.05). Serum irisin level was significantly increased in the middle-aged/older training group after the intervention period (P < 0.01), but not in the young training group. Furthermore, in the middle-aged/older training group, the endurance training-induced reduction ...Continue Reading

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Citations

May 24, 2016·EBioMedicine·Hong TangWeizhen Zhang
Oct 14, 2017·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S BuscemiC Giordano
Sep 22, 2017·Eating and Weight Disorders : EWD·Silvio BuscemiCarla Giordano
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Dec 21, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Kenichiro InoueMotoyuki Iemitsu
Apr 23, 2020·Journal of Clinical Medicine·Laurent MaïmounAriane Sultan
Jun 4, 2020·International Journal of Environmental Research and Public Health·Dae Yun SeoJin Han
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Jul 3, 2021·International Journal of Molecular Sciences·Johannes BurtscherNadège Zanou

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Methods Mentioned

BETA
x-ray
ELISA

Software Mentioned

Power and Size Calculations
Slice
- matic
SPSS
Tomovision
- o
StatView

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