Energetics of Blood Flow in Cardiovascular Disease: Concept and Clinical Implications of Adverse Energetics in Patients With a Fontan Circulation

Circulation
Friso M RijnbergArno A W Roest

Abstract

Visualization and quantification of the adverse effects of distorted blood flow are important emerging fields in cardiology. Abnormal blood flow patterns can be seen in various cardiovascular diseases and are associated with increased energy loss. These adverse energetics can be measured and quantified using 3-dimensional blood flow data, derived from computational fluid dynamics and 4-dimensional flow magnetic resonance imaging, and provide new, promising hemodynamic markers. In patients with palliated single-ventricular heart defects, the Fontan circulation passively directs systemic venous return to the pulmonary circulation in the absence of a functional subpulmonary ventricle. Therefore, the Fontan circulation is highly dependent on favorable flow and energetics, and minimal energy loss is of great importance. A focus on reducing energy loss led to the introduction of the total cavopulmonary connection (TCPC) as an alternative to the classical Fontan connection. Subsequently, many studies have investigated energy loss in the TCPC, and energy-saving geometric factors have been implemented in clinical care. Great advances have been made in computational fluid dynamics modeling and can now be done in 3-dimensional patient-spe...Continue Reading

References

Mar 30, 1999·The Journal of Thoracic and Cardiovascular Surgery·A C LardoE G Cape
Jul 3, 1999·The Annals of Thoracic Surgery·A GerdesH H Sievers
Oct 30, 1999·The Annals of Thoracic Surgery·A E EnsleyA P Yoganathan
Feb 15, 2001·Pediatric Cardiology·R J AscuittoN T Ross-Ascuitto
Mar 10, 2001·Physiological Measurement·S CavalcantiC F Marcelletti
Apr 17, 2002·Journal of Biomechanics·G BolzonG D'Avenio
Aug 31, 2002·The Journal of Thoracic and Cardiovascular Surgery·Antonio AmodeoRoberto M Di Donato
May 5, 2005·Annals of Biomedical Engineering·Kerem PekkanAjit P Yoganathan
May 21, 2005·Cardiology in the Young·Antonio AmodeoRoberto M Di Donato
May 28, 2005·The Annals of Thoracic Surgery·Diane A de ZélicourtAjit P Yoganathan
Mar 17, 2006·Pediatric Cardiology·K R MoyleT L Gentles
Apr 4, 2006·The Journal of Thoracic and Cardiovascular Surgery·Diane A de ZélicourtAjit P Yoganathan
Jun 14, 2006·Circulation·Yoram Richter, Elazer R Edelman
Dec 16, 2006·Annals of Biomedical Engineering·Alison L MarsdenCharles A Taylor
May 29, 2007·The Annals of Thoracic Surgery·Dennis D SoerensenAjit P Yoganathan
Jul 21, 2007·Annals of Biomedical Engineering·Chang WangAjit P Yoganathan
Feb 23, 2008·The Annals of Thoracic Surgery·Alessandro GiardiniFernando M Picchio
Jul 5, 2008·Journal of the American College of Cardiology·Stephen M ParidonUNKNOWN Pediatric Heart Network Investigators
Oct 22, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Kartik S SundareswaranAjit P Yoganathan
Oct 29, 2008·The Journal of Thoracic and Cardiovascular Surgery·Cary W AkinsAjit P Yoganathan
Feb 3, 2009·The Journal of Thoracic and Cardiovascular Surgery·Alison L MarsdenJeffrey A Feinstein
Feb 19, 2009·Annals of Biomedical Engineering·Lakshmi P DasiAjit P Yoganathan
Mar 5, 2009·The Journal of Thoracic and Cardiovascular Surgery·Lakshmi P DasiAjit P Yoganathan
Jul 28, 2009·The Annals of Thoracic Surgery·Keiichi ItataniMasahiro Ishii
Apr 24, 2010·Congenital Heart Disease·Alison L MarsdenJeffrey A Feinstein
Jul 14, 2010·The Journal of Thoracic and Cardiovascular Surgery·Lakshmi P DasiAjit P Yoganathan
Feb 1, 2011·The Journal of Thoracic and Cardiovascular Surgery·Keiichi ItataniMasahiro Ishii
Oct 5, 2011·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·A BarettaUNKNOWN Modeling of Congenital Hearts Alliance (MOCHA) Investigators

❮ Previous
Next ❯

Citations

Sep 7, 2019·Artificial Organs·Dmitry TelyshevSergey Selishchev
Mar 4, 2020·Pediatric Cardiology·William N EvansHumberto Restrepo
Dec 21, 2019·Heart·Evangeline WarmerdamHeynric B Grotenhuis
Mar 14, 2020·American Journal of Physiology. Heart and Circulatory Physiology·Michal SchäferMichael V Di Maria
Mar 11, 2020·Annual Review of Biomedical Engineering·Gilles SoulatMichael Markl
May 8, 2020·Pediatric Cardiology·Zhenglun Alan WeiMahesh Kappanayil
Sep 2, 2020·European Radiology·Judy Rizk
Sep 4, 2020·Asian Cardiovascular & Thoracic Annals·Rabin Gerrah, Stephen J Haller
May 7, 2020·Annals of Biomedical Engineering·Zhenglun WeiAjit P Yoganathan
Dec 28, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Friso M RijnbergArno A W Roest
May 1, 2019·Interactive Cardiovascular and Thoracic Surgery·Friso M RijnbergMark G Hazekamp
Oct 5, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Andrew L ChengJohn C Wood
Nov 9, 2020·Pediatric Cardiology·John M KellyKan N Hor
Feb 9, 2021·Biosensors & Bioelectronics·Tucker StuartPhilipp Gutruf
Mar 4, 2021·The Journal of Thoracic and Cardiovascular Surgery·Michal SchäferMax B Mitchell
Aug 10, 2020·Computers in Biology and Medicine·Christian WinklerUlrike Herberg
Apr 8, 2021·Journal of the Royal Society, Interface·Friso M RijnbergArno A W Roest
May 13, 2021·Seminars in Thoracic and Cardiovascular Surgery·Jan Hinnerk HansenAnselm Uebing
Jul 24, 2021·Npj Regenerative Medicine·Erica L SchwarzChristopher K Breuer
Nov 9, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Friso M RijnbergArno A W Roest

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.