Energy and nitrogenous waste from glutamate/glutamine catabolism facilitates acute osmotic adjustment in non-neuroectodermal branchial cells.

Scientific Reports
Pei-Chen HuangYung-Che Tseng

Abstract

Maintenance of homeostasis is one of the most important physiological responses for animals upon osmotic perturbations. Ionocytes of branchial epithelia are the major cell types responsible for active ion transport, which is mediated by energy-consuming ion pumps (e.g., Na+-K+-ATPase, NKA) and secondary active transporters. Consequently, in addition to osmolyte adjustments, sufficient and immediate energy replenishment is essenttableial for acclimation to osmotic changes. In this study, we propose that glutamate/glutamine catabolism and trans-epithelial transport of nitrogenous waste may aid euryhaline teleosts Japanese medaka (Oryzias latipes) during acclimation to osmotic changes. Glutamate family amino acid contents in gills were increased by hyperosmotic challenge along an acclimation period of 72 hours. This change in amino acids was accompanied by a stimulation of putative glutamate/glutamine transporters (Eaats, Sat) and synthesis enzymes (Gls, Glul) that participate in regulating glutamate/glutamine cycling in branchial epithelia during acclimation to hyperosmotic conditions. In situ hybridization of glutaminase and glutamine synthetase in combination with immunocytochemistry demonstrate a partial colocalization of olgl...Continue Reading

References

Jan 1, 1992·Progress in Brain Research·A C YuL F Eng
Jul 1, 1990·The American Journal of Physiology·P A Wright, M A Knepper
Jan 1, 1984·Journal of Neurochemistry·F Fonnum
Nov 1, 1981·Kidney International·V PhromphetcharatT C Welbourne
Dec 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·R C Hudson, R M Daniel
Mar 29, 2000·The Journal of Nutrition·J T Brosnan
May 23, 2001·Progress in Neurobiology·N C Danbolt
Dec 12, 2001·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·G Boeuf, P Payan
Feb 13, 2003·Cell Biochemistry and Function·Philip NewsholmeRui Curi
Dec 10, 2003·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Shigehisa HiroseYoshio Takei
Dec 10, 2003·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Neil HazonCraig E Franklin
May 18, 2004·Neurochemistry International·Leif Hertz
Nov 16, 2004·Trends in Neurosciences·Leif Hertz, H Ronald Zielke
Dec 27, 2005·The Veterinary Journal·Simon R Platt
Feb 1, 2007·The Journal of Membrane Biology·M D McDonaldP J Walsh
Feb 24, 2007·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Sergio PolakofJosé L Soengas
Mar 17, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Yung-Che TsengPung-Pung Hwang
May 23, 2007·The Journal of Experimental Biology·J S BystrianskyJ S Ballantyne
Aug 11, 2007·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Pung-Pung Hwang, Tsung-Han Lee
Jun 10, 2008·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Yung-Che Tseng, Pung-Pung Hwang
May 22, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Yung-Che TsengPung-Pung Hwang
Jun 26, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Erin M RoseDavid R Hampson
Nov 27, 2009·American Journal of Physiology. Cell Physiology·Shu-Chen WuLi-Yih Lin
Dec 22, 2009·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Shit F ChewYuen K Ip
Jan 26, 2010·Brain Research Reviews·Volker Eulenburg, Jesús Gomeza
Aug 25, 2010·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Marvin H Braun, Steve F Perry
Dec 3, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Yung-Che TsengPung-Pung Hwang
Feb 26, 2011·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Janet GenzMartin Grosell
Jan 1, 2010·Frontiers in Physiology·Yuen K Ip, Shit F Chew
Mar 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Andrew WhiteheadFernando Galvez
Apr 1, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Pung-Pung HwangLi-Yih Lin
Jul 8, 2011·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Jonathan M Whittamore
Aug 23, 2011·Neurochemistry International·Zila Martínez-LozadaArturo Ortega
Oct 14, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Tin-Han ShihLi-Yih Lin
Dec 14, 2011·Cell Metabolism·Mireille BélangerPierre J Magistretti
Jan 10, 2012·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Wataru TakagiSusumu Hyodo
Jun 12, 2012·Respiratory Physiology & Neurobiology·M Danielle McDonaldPatrick J Walsh
Sep 18, 2012·Respiratory Physiology & Neurobiology·Agnieszka K DymowskaGreg G Goss
Sep 27, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Shelly Abad CruzPung-Pung Hwang
Feb 19, 2013·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Yung-Che TsengPung-Pung Hwang
Apr 10, 2013·Pflügers Archiv : European journal of physiology·Pung-Pung Hwang, Ming-Yi Chou

❮ Previous
Next ❯

Citations

Apr 30, 2021·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Kathleen M MunleyFernando Galvez

❮ Previous
Next ❯

Methods Mentioned

BETA
Assay
PCR
in vitro transcription
dot blot
Fluorescence
antisense oligonucleotides
deamination

Software Mentioned

Ensembl Genome Browser system
BLAST
ENSEMBL browser
ClustalX
BLASTx
/ BLAT
Ensembl
GraphPad Prism

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.