Energy balance and body-weight stability: impact of gene-environment interactions

The British Journal of Nutrition
Angelo TremblayC Bouchard

Abstract

Studies of monozygotic twins in the context of overfeeding and energy deficit experiments have shown that gene-environment interactions affect energy balance. From a clinical standpoint, this implies that some individuals are more susceptible to body-weight gain or loss than others because of genetic differences. This opens new perspectives in predictive medicine. In the future, health professionals should be able to count on early diagnosis of individuals at risk for developing long-term metabolic problems and obesity or for not responding adequately to clinical interventions. However, before predictive medicine is in a position to contribute significantly to prevention or treatment of patients, an enormous amount of work has to be done to identify all genetic and environmental factors of relevance, and their network of interactions.

References

Nov 1, 1992·The American Journal of Clinical Nutrition·A TremblayC Bouchard
May 24, 1990·The New England Journal of Medicine·C BouchardG Fournier
May 1, 1989·The American Journal of Clinical Nutrition·A TremblayC Bouchard
Jun 1, 1989·Physiology & Behavior·K TokunagaR Schemmel
Feb 1, 1987·Journal of Applied Physiology·A TremblayC Bouchard
Jan 1, 1987·European Journal of Applied Physiology and Occupational Physiology·E T PoehlmanC Bouchard
Aug 5, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·E DoucetA Tremblay
Mar 14, 2003·Obesity Research·Yvon C ChagnonClaude Bouchard
Sep 1, 1994·Obesity Research·C BouchardG Fournier

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Citations

Mar 15, 2006·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S LiG S Berenson
May 31, 2018·Critical Reviews in Food Science and Nutrition·Maninder Meenu, Baojun Xu
Jun 1, 2012·Clinical Obesity·Y FreedhoffN Christou
Oct 14, 2006·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S B HeymsfieldA Pietrobelli
Nov 11, 2008·Obesity·Femke RuttersMargriet S Westerterp-Plantenga
Jan 12, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·F RuttersM S Westerterp-Plantenga
Nov 30, 2014·Journal of Translational Medicine·Laura Di RenzoAntonino De Lorenzo
Apr 20, 2016·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Fidelia A A DakeSamuel N A Codjoe
Feb 6, 2020·Physiology & Behavior·Angelos Vlahoyiannis, Artemissia-Phoebe Nifli
May 4, 2005·Journal of the American Dietetic Association·George L Blackburn, Belinda A Waltman
Apr 23, 2010·Patient Education and Counseling·Femke RuttersMargriet S Westerterp-Plantenga

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