Energy expenditure of adult male rhesus monkeys during the first 30 mo of dietary restriction

The American Journal of Physiology
Jon RamseyJoseph Kemnitz

Abstract

Energy expenditure, activity, and body composition were measured in 30 adult male rhesus monkeys used in a study having the long-term goal of determining the effects of moderate dietary restriction (DR) on aging. All animals were fed a defined diet, with the restricted animals maintained at approximately 70% of the caloric intakes of the controls. After 12 mo of DR, body fat mass of restricted monkeys was 33% less than that of controls (P = 0.004), whereas lean body mass differences were not present until after 24 mo. At the 24- and 30-mo assessments, nighttime energy expenditure was significantly reduced (P < 0.01) in the restricted compared with control monkeys after adjustment for lean body mass differences, whereas morning, afternoon, and total energy expenditure were not significantly different (P > 0.05). No significant differences (P > 0.05) in activity were noticed between treatment groups at any time point. DR resulted in a prolonged decrease in resting energy expenditure, which could contribute to the possible life-extending action of this treatment.

References

Sep 1, 1992·The Journal of Nutrition·W S Lynn, J C Wallwork
Apr 1, 1992·Metabolism: Clinical and Experimental·A Luke, D A Schoeller
Jan 1, 1991·Comparative Biochemistry and Physiology. A, Comparative Physiology·J Luz, M A Griggio
Jun 1, 1990·The American Journal of Clinical Nutrition·R B MazessJ Hanson
Jul 25, 1990·Biochimica Et Biophysica Acta·M D Brand
Dec 1, 1988·The Journal of Nutrition·D G BurrinC L Ferrell
Jun 1, 1989·Mechanisms of Ageing and Development·S Laganiere, B P Yu
Jan 1, 1988·Progress in Lipid Research·F L Hoch
Nov 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·D Harman
Dec 1, 1980·Journal of Animal Science·R L BaldwinM Sharp
Mar 1, 1995·Journal of Animal Science·H C FreetlyA L Goetsch
Jan 1, 1993·The Journal of Nutrition·D M Gonzales-PachecoS S Alpert
Apr 30, 1996·Proceedings of the National Academy of Sciences of the United States of America·M A LaneG S Roth
Jul 5, 1996·Science·R S Sohal, R Weindruch

❮ Previous
Next ❯

Citations

Jun 29, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·S B RobertsS Shapses
May 12, 2005·American Journal of Physiology. Endocrinology and Metabolism·Lisa BevilacquaMary-Ellen Harper
Aug 10, 2006·American Journal of Physiology. Endocrinology and Metabolism·Aarthi RamanDale A Schoeller
Feb 25, 2011·Proceedings. Biological Sciences·Chen HouAviv Bergman
Aug 16, 2011·Molecular Aspects of Medicine·John R Speakman, Sharon E Mitchell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.