Energy loss in the left ventricle obtained by vector flow mapping as a new quantitative measure of severity of aortic regurgitation: a combined experimental and clinical study

European Heart Journal Cardiovascular Imaging
Marie StugaardS Nakatani

Abstract

In aortic regurgitation (AR), energy loss (EL) produced by inefficient turbulent flow may be a burden to the heart predicting decompensation. We attempted to quantify EL in AR induced in an acute dog model and in patients with chronic AR using novel echocardiographic method vector flow mapping (VFM). In 11 anaesthetized open-chest dogs, AR was induced by distorting the aortic valve with a pigtail catheter, in totally 20 cases. Regurgitant fraction was determined using pulsed Doppler echocardiography, <30% considered mild to moderate (Group 1, n = 11) and ≥30% moderate to severe (Group 2, n = 9). The clinical study consisted of 22 patients with various degrees of AR; 11 mild to moderate (Group 1) and 11 moderate to severe (Group 2), and compared with 12 normals. VFM is based on continuity equation applied to colour Doppler and speckle tracking velocities, acquired from apical long-axis image. EL was calculated frame by frame, averaged from three beats. In the dog study, diastolic EL increased significantly with severity of AR (baseline vs. Group 1 vs. Group 2: 3.8 ± 1.6 vs. 13.0 ± 5.0 vs. 22.4 ± 14.0 [J/(m s)], ANOVA P = 0.0001). Similar to dogs, diastolic EL also increased in humans by the severity of AR (control vs. Group 1 vs...Continue Reading

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Citations

Aug 13, 2015·Journal of cardiology·Taiyu Hayashi, Keiichi Itatani
Apr 4, 2015·European Heart Journal Cardiovascular Imaging·Gianni Pedrizzetti, Partho P Sengupta
Jun 11, 2016·Interactive Cardiovascular and Thoracic Surgery·Weimin ZhangLe Mao
Apr 3, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yue ZhongLi Rao
Mar 10, 2017·Journal of Cardiothoracic and Vascular Anesthesia·Koichi AkiyamaTeiji Sawa
Apr 2, 2017·Biomechanics and Modeling in Mechanobiology·Vivek VasudevanChoon Hwai Yap
Apr 22, 2017·European Heart Journal·Carlos E RuizUNKNOWN Paravalvular Leak Academic Research Consortium
Sep 21, 2017·General Thoracic and Cardiovascular Surgery·Keiichi ItataniHitoshi Yaku
Jan 17, 2017·Annals of Biomedical Engineering·Ikechukwu OkaforAjit P Yoganathan
Jan 11, 2017·BMC Cardiovascular Disorders·Koichi AkiyamaTeiji Sawa
Mar 16, 2017·Journal of Magnetic Resonance Imaging : JMRI·Merih CibisTino Ebbers
May 21, 2019·Frontiers in Physiology·Yolanda BenitoJavier Bermejo
Nov 27, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Shohei YoshidaYoshiki Sawa
Oct 2, 2020·Cardiovascular Engineering and Technology·Chloé PapollaRégis Rieu
Jul 22, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Zhongxiu ChenLi Rao
Nov 22, 2020·Computer Methods and Programs in Biomedicine·Peiran ChenMassimo Mischi
Feb 17, 2021·PloS One·Philip C WienerGregg S Pressman
Mar 6, 2021·Interactive Cardiovascular and Thoracic Surgery·Hisayuki HonguHitoshi Yaku
May 11, 2021·Surgical Technology International·Stefan EngelhardMichel M P J Reijnen
Jun 29, 2021·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Noriko Oyama-ManabeOsamu Manabe
Jun 29, 2021·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Hirokazu KomoriyamaToshihisa Anzai
Jul 15, 2021·Echocardiography·Martina AvesaniXavier Iriart

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