Energy metabolism in patients with acute and chronic liver disease

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
B SchneeweissG Kleinberger

Abstract

Energy expenditure and substrate oxidation rate for fat, glucose and protein were evaluated by indirect calorimetry in 20 normal individuals, 35 patients with acute hepatitis and 22 patients with biopsy-proven alcoholic cirrhosis in the postabsorptive state. Measurements were done in the resting state after an overnight fast (10 to 12 hr). Oxygen consumption (ml/min/1.73 m2) in normal subjects, in patients with acute hepatitis and in patients with cirrhosis was 206.5 +/- 4.0 (mean +/- S.E.M.), 216.4 +/- 4.7 and 228.8 +/- 7.1 (p less than 0.05 vs. controls), respectively. When related to body surface area (kcal/min/1.73 m2), resting energy expenditure did not differ between normal subjects (0.98 +/- 0.02), patients with acute hepatitis (1.03 +/- 0.02) and cirrhotic patients (1.06 +/- 0.03). However, when related to 24-hr urinary creatinine excretion as an estimate of lean body mass, energy expenditure was increased in cirrhosis (p less than 0.0001). In cirrhosis an inverse association between the severity of liver disease according to Pugh and oxygen consumption and resting energy expenditure was found. In cirrhotic patients the percentages of total calories derived from fat (86% +/- 5%), carbohydrate (2% +/- 4%) and protein (12...Continue Reading

References

Mar 1, 1976·Pediatric Research·D PicouN Poulter
Apr 1, 1976·Journal of Applied Physiology·J H WilmoreA C Norton
Dec 1, 1976·The American Journal of Clinical Nutrition·G B Forbes, G J Bruining
Oct 1, 1988·The American Journal of Clinical Nutrition·W J CochranW J Klish
Jul 1, 1986·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K D MullenS C Kalhan
Sep 1, 1986·The American Journal of Clinical Nutrition·S S JhangianiC S Pitchumoni
Aug 1, 1988·Journal of Hepatology·R MoreauC Sicot
Mar 1, 1988·Metabolism: Clinical and Experimental·E Ferrannini
May 1, 1987·JPEN. Journal of Parenteral and Enteral Nutrition·R L ShanbhogueG L Blackburn
Nov 1, 1986·Kidney International·F J MonteonJ D Kopple
Aug 1, 1973·The British Journal of Surgery·R N PughR Williams
Aug 1, 1972·Metabolism: Clinical and Experimental·G GreatrexF D Moore
Mar 1, 1970·Journal of Applied Physiology·R A KreisbergC K Meador
Dec 24, 1970·The New England Journal of Medicine·P FeligG Klatskin
Aug 1, 1983·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·K N Frayn
Nov 1, 1983·The Journal of Clinical Investigation·O E OwenG Boden
Jul 1, 1984·The American Journal of Clinical Nutrition·A M Roza, H M Shizgal
Sep 1, 1982·Anesthesiology·M C DamaskJ M Kinney
Mar 1, 1983·The American Journal of Clinical Nutrition·S B HeymsfieldS Moffitt
Sep 26, 1963·Annals of the New York Academy of Sciences·E C ANDERSON

❮ Previous
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Citations

Feb 14, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A V GrecoG Gasbarrini
Aug 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A M Madden, M Y Morgan
Nov 1, 1994·Digestive Diseases and Sciences·F PerriA Andriulli
Aug 7, 2002·International Journal of Cardiology·Mathias Plauth, Elke-Tatjana Schütz
Jul 1, 1997·Journal of Hepatology·J Kondrup, M J Müller
Mar 8, 2002·Nutrition·Masahiro TajikaHisataka Moriwaki
Mar 8, 2002·Nutrition·Ronnie Tung-Ping Poon, Sheung-Tat Fan
Oct 1, 1996·Baillière's Clinical Endocrinology and Metabolism·M R Charlton
Apr 4, 2006·Nature Clinical Practice. Gastroenterology & Hepatology·Anne S Henkel, Alan L Buchman
Feb 1, 1995·Journal of the American College of Nutrition·S HirschD Bunout
Feb 7, 2001·Critical Care Medicine·T S WalshA Lee
Apr 7, 2007·Current Opinion in Clinical Nutrition and Metabolic Care·Sudeep Khanna, Sarath Gopalan
Jan 1, 1993·Journal of Gastroenterology and Hepatology·D H CrawfordR W Shepherd
Jan 1, 1996·Journal of Gastroenterology and Hepatology·J GeorgeG C Farrell
Apr 2, 2009·European Journal of Endocrinology·Peter Holland-FischerHenning Grønbaek
Oct 9, 2008·Canadian Journal of Physiology and Pharmacology·Hanumantha Rao Balaji Raghavendran, Periasamy Srinivasan
Jan 1, 2010·Journal of Nutritional Science and Vitaminology·Yoichi TerakuraHisataka Moriwaki
Jun 14, 2002·Indian Journal of Pediatrics·Ashish BavdekarAnand Pandit
Nov 28, 2013·Clinics in Liver Disease·Vignan Manne, Sammy Saab
Nov 1, 1993·Gastroenterology·B SchneeweissG Grimm
Nov 13, 2015·European Journal of Gastroenterology & Hepatology·César Prieto-FríasJorge Quiroga
Mar 28, 2008·Gastroentérologie Clinique Et Biologique·S BuyseF Joly
Jun 23, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Akinobu Kato, Kazuyuki Suzuki
Apr 23, 2013·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Tatsunori HanaiHisataka Moriwaki
Oct 30, 2013·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Eri UranoEiji Takeda
Apr 1, 1997·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·M PlauthUNKNOWN ESPEN Consensus Group
Aug 16, 2006·Transplantation Proceedings·A L Buchman
Dec 3, 1998·Gastroenterology·E BugianesiA McCullough
Jun 1, 1994·Journal of Hepatology·G L KayeN McIntyre
Sep 1, 1992·Journal of Hepatology·A ThörneS Eriksson
Apr 19, 2015·Critical Care : the Official Journal of the Critical Care Forum·Ulrike HolzingerBruno Schneeweiß
Jul 16, 2016·Journal of Animal Physiology and Animal Nutrition·M ThesE Kienzle
Jan 5, 2011·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Carla Maria AvesaniLilian Cuppari
Nov 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S H QuarfordtY Yamaguchi

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