Engagement with INSPIRE, an Online Program for Hematopoietic Cell Transplantation Survivors

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Karen L SyrjalaJean C Yi

Abstract

In a secondary analysis of a randomized controlled trial (RCT), we examined participants' engagement with INSPIRE, a personalized online program for hematopoietic cell transplantation (HCT) survivors that focuses on cancer-related distress, depression, fatigue, and health care needs. We approached all adult, 3- to 18-year HCT survivors treated for hematologic malignancy without relapse or second cancer in the previous 2 years for participation in an RCT with either immediate or delayed access to INSPIRE. Participants with immediate access could view the online material at any time. Data included page view tracking, medical records, and patient-reported outcomes, including the Short Form 36 and Cancer and Treatment Distress (CTXD) measures. Of 1322 eligible HCT survivors, 771 (58%) completed the baseline assessment, and 451 received immediate INSPIRE access and were included in analyses. The cohort was 56% male, with a mean age of 52 ± 12.2 years, and 26% received an autologous transplant. Most (77%) logged into the INSPIRE site at least once, and 48% viewed ≥8 pages. Survivors who viewed ≥2 pages were more likely to be age ≥40 years (relative risk [RR], 1.41; 95% confidence interval [CI], 1.10 to 1.80), to be female (RR, 1.22; ...Continue Reading

Citations

Jan 10, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Salene M W JonesKaren L Syrjala
Nov 16, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jaime M PreusslerKaren L Syrjala
Jan 10, 2021·Journal of Cancer Survivorship : Research and Practice·Kristina Holmegaard NørskovKaren L Syrjala
Aug 2, 2021·Journal of the American Medical Informatics Association : JAMIA·Sean P MiklesArlene E Chung
Dec 11, 2021·Hematology·David Buchbinder, Nandita Khera

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